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Drug Eruption and Interactions - PHARMACEUTICAL REVIEW

Drug Eruption and Interactions - PHARMACEUTICAL REVIEW

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CIMETIDINE<br />

Trade names: Apo-Cimetidine; Azucimet; Blocan; Cimedine;<br />

Cimehexal; Ciuk; Dyspamet; Novocimetine; Nu-Cimet; Peptol;<br />

Stomedine; Tagamet (GSK); Ulcedine; Zymerol<br />

Indications: Duodenal ulcer<br />

Category: Histamine H2 receptor antagonist<br />

Half-life: 2 hours<br />

Clinically important, potentially hazardous interactions<br />

with: alfuzosin, aminophylline, anisindione, anticoagulants,<br />

buprenorphine, butorphanol, caffeine, carmustine, clobazam,<br />

cocoa, dicumarol, dofetilide, duloxetine, epirubicin, fentanyl,<br />

floxuridine, fluorouracil, galantamine, hydromorphone,<br />

itraconazole, ketoconazole, lidocaine, midazolam, morphine,<br />

narcotic analgesics, oxycodone, pentazocine, phenytoin,<br />

posaconazole, prednisone, propranolol, sufentanil, theophylline,<br />

tolazoline, warfarin, xanthines, zaleplon, zolmitriptan, zolpidem<br />

Reactions<br />

Skin<br />

Acne<br />

Angioedema (

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