Drug Eruption and Interactions - PHARMACEUTICAL REVIEW
Drug Eruption and Interactions - PHARMACEUTICAL REVIEW Drug Eruption and Interactions - PHARMACEUTICAL REVIEW
(1989): Rosen C, Semin Dermatol 8, 149 (1986): Lovell CR+, Contact Dermatitis 14, 290 (1982): Amblard P+, Ann Dermatol Venereol (French) 109, 225 Phototoxicity (1997): Eberlein-Konig B+, Dermatology 194, 131 Pigmentation (
122 CHLORPROPAMIDE reactions such as toxic epidermal necrolysis and Stevens–Johnson syndrome CHLORTETRACYCLINE Trade names: Aureomicina; Aureomycin Indications: Various infections due to susceptible organisms Category: Antibiotic, tetracycline Half-life: N/A Skin Edema (topical) Erythema (topical) Irritation (topical) Photosensitivity Pruritus (topical) Rash (sic) (topical) Xerosis (topical) Mucosal Xerostomia (ophthalmic) Eyes Corneal edema Ocular burning (topical) Ocular stinging (topical) Reactions CHLORTHALIDONE Trade names: Combipres; Higroton; Hydro-Long; Hygroton; Hypertol; Igroton; Tenoretic (AstraZeneca); Thalidone; Thalitone (Monarch); Uridon Indications: Hypertension Category: Diuretic, thiazide Half-life: 35–50 hours Clinically important, potentially hazardous interactions with: digoxin, lithium, zinc Combipres is chlorthalidone and clonidine Reactions Skin Angioedema (2006): Piller LB+, J Clin Hypertens 8(9), 649 (Greenwich) (15%) Erythema multiforme Exanthems Exfoliative dermatitis Lupus erythematosus Necrotizing vasculitis Photosensitivity (1–10%) (1989): Baker EJ+, JAmAcadDermatol21, 1026 (1988): Lehmann P+, Hautarzt (German) 39, 38 Psoriasis (1987): Wolf R+, Cutis 40, 162 Purpura (
- Page 146 and 147: BLEOMYCIN Synonyms: bleo; BLM Trade
- Page 148 and 149: BLOODROOT Scientific name: Sanguina
- Page 150 and 151: Punctate keratitis (2004): Northing
- Page 152 and 153: BROMFENAC Trade name: Xibrom (ISTA
- Page 154 and 155: Erythema multiforme (
- Page 156 and 157: Myalgia/Myositis/Myopathy/Myotoxici
- Page 158 and 159: (1989): Ackerman WE+, Can J Anaesth
- Page 160 and 161: CALFACTANT Trade name: Infasurf (Fo
- Page 162 and 163: CAPSICUM Scientific names: Capsicum
- Page 164 and 165: Lupus erythematosus (2002): Ratliff
- Page 166 and 167: Corneal edema Eyelid twitching Kera
- Page 168 and 169: Stevens-Johnson syndrome (1-10%) (2
- Page 170 and 171: Porphyria variegata (2001): Grieco
- Page 172 and 173: (1983): Rollings HE+, Curr Ther Res
- Page 174 and 175: Dermatitis (1986): Hirata M+, Kokyu
- Page 176 and 177: Other Anaphylactoid reactions/Anaph
- Page 178 and 179: Other Anaphylactoid reactions/Anaph
- Page 180 and 181: Other Anaphylactoid reactions/Anaph
- Page 182 and 183: Candidiasis (
- Page 184 and 185: Herpes zoster (
- Page 186 and 187: Hypersensitivity Injection-site pai
- Page 188 and 189: Other Abdominal pain (25%) Anaphyla
- Page 190 and 191: CHLORAMBUCIL Trade names: Chloramin
- Page 192 and 193: (1992): Ramselaar CG+, Br J Urol 70
- Page 194 and 195: (1997): Selvaag E, Ann Trop Pediatr
- Page 198 and 199: CHOLESTYRAMINE Trade names: Chol-Le
- Page 200 and 201: CIMETIDINE Trade names: Apo-Cimetid
- Page 202 and 203: (2000): Sharobeem KM+, J Cardiovasc
- Page 204 and 205: (1997): Carrasco JM+, Ann Pharmacot
- Page 206 and 207: CITALOPRAM Synonym: nitalapram Trad
- Page 208 and 209: CLEMASTINE Trade names: Aller-Eze;
- Page 210 and 211: Other Hypersensitivity (2002): Somm
- Page 212 and 213: CLOMIPRAMINE Trade names: Anafranil
- Page 214 and 215: CLOPIDOGREL Trade name: Plavix (Bri
- Page 216 and 217: Eczema (
- Page 218 and 219: (1997): Thaler D, Monona, WI (from
- Page 220 and 221: COCOA Scientific names: Theobroma c
- Page 222 and 223: COLESEVELAM Trade name: Welchol (Sa
- Page 224 and 225: CORDYCEPS Scientific name: Cordycep
- Page 226 and 227: CYCLAMATE Trade name: Sucaryl (Abbo
- Page 228 and 229: Inappropriate secretion of antidiur
- Page 230 and 231: (1996): Cox NH, Clin Exp Dermatol 2
- Page 232 and 233: (2007): Lim AK+, Intern Med J 37(1)
- Page 234 and 235: (1989): Kerker BJ+, Semin Dermatol
- Page 236 and 237: Pruritus (1-10%) Rash (sic) (1-10%)
- Page 238 and 239: (1988): Tham SN+, Singapore Med J 2
- Page 240 and 241: DASATINIB Synonym: BMS354825 Trade
- Page 242 and 243: Other Anaphylactoid reactions/Anaph
- Page 244 and 245: (1980): Miescher PA+, Clin Haematol
122 CHLORPROPAMIDE<br />
reactions such as toxic epidermal necrolysis <strong>and</strong> Stevens–Johnson<br />
syndrome<br />
CHLORTETRACYCLINE<br />
Trade names: Aureomicina; Aureomycin<br />
Indications: Various infections due to susceptible organisms<br />
Category: Antibiotic, tetracycline<br />
Half-life: N/A<br />
Skin<br />
Edema (topical)<br />
Erythema (topical)<br />
Irritation (topical)<br />
Photosensitivity<br />
Pruritus (topical)<br />
Rash (sic) (topical)<br />
Xerosis (topical)<br />
Mucosal<br />
Xerostomia (ophthalmic)<br />
Eyes<br />
Corneal edema<br />
Ocular burning (topical)<br />
Ocular stinging (topical)<br />
Reactions<br />
CHLORTHALIDONE<br />
Trade names: Combipres; Higroton; Hydro-Long; Hygroton;<br />
Hypertol; Igroton; Tenoretic (AstraZeneca); Thalidone; Thalitone<br />
(Monarch); Uridon<br />
Indications: Hypertension<br />
Category: Diuretic, thiazide<br />
Half-life: 35–50 hours<br />
Clinically important, potentially hazardous interactions<br />
with: digoxin, lithium, zinc<br />
Combipres is chlorthalidone <strong>and</strong> clonidine<br />
Reactions<br />
Skin<br />
Angioedema<br />
(2006): Piller LB+, J Clin Hypertens 8(9), 649 (Greenwich) (15%)<br />
Erythema multiforme<br />
Exanthems<br />
Exfoliative dermatitis<br />
Lupus erythematosus<br />
Necrotizing vasculitis<br />
Photosensitivity (1–10%)<br />
(1989): Baker EJ+, JAmAcadDermatol21, 1026<br />
(1988): Lehmann P+, Hautarzt (German) 39, 38<br />
Psoriasis<br />
(1987): Wolf R+, Cutis 40, 162<br />
Purpura (