Drug Eruption and Interactions - PHARMACEUTICAL REVIEW

Drug Eruption and Interactions - PHARMACEUTICAL REVIEW Drug Eruption and Interactions - PHARMACEUTICAL REVIEW

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(1989): Rosen C, Semin Dermatol 8, 149 (1986): Lovell CR+, Contact Dermatitis 14, 290 (1982): Amblard P+, Ann Dermatol Venereol (French) 109, 225 Phototoxicity (1997): Eberlein-Konig B+, Dermatology 194, 131 Pigmentation (

122 CHLORPROPAMIDE reactions such as toxic epidermal necrolysis and Stevens–Johnson syndrome CHLORTETRACYCLINE Trade names: Aureomicina; Aureomycin Indications: Various infections due to susceptible organisms Category: Antibiotic, tetracycline Half-life: N/A Skin Edema (topical) Erythema (topical) Irritation (topical) Photosensitivity Pruritus (topical) Rash (sic) (topical) Xerosis (topical) Mucosal Xerostomia (ophthalmic) Eyes Corneal edema Ocular burning (topical) Ocular stinging (topical) Reactions CHLORTHALIDONE Trade names: Combipres; Higroton; Hydro-Long; Hygroton; Hypertol; Igroton; Tenoretic (AstraZeneca); Thalidone; Thalitone (Monarch); Uridon Indications: Hypertension Category: Diuretic, thiazide Half-life: 35–50 hours Clinically important, potentially hazardous interactions with: digoxin, lithium, zinc Combipres is chlorthalidone and clonidine Reactions Skin Angioedema (2006): Piller LB+, J Clin Hypertens 8(9), 649 (Greenwich) (15%) Erythema multiforme Exanthems Exfoliative dermatitis Lupus erythematosus Necrotizing vasculitis Photosensitivity (1–10%) (1989): Baker EJ+, JAmAcadDermatol21, 1026 (1988): Lehmann P+, Hautarzt (German) 39, 38 Psoriasis (1987): Wolf R+, Cutis 40, 162 Purpura (

(1989): Rosen C, Semin Dermatol 8, 149<br />

(1986): Lovell CR+, Contact Dermatitis 14, 290<br />

(1982): Amblard P+, Ann Dermatol Venereol (French) 109, 225<br />

Phototoxicity<br />

(1997): Eberlein-Konig B+, Dermatology 194, 131<br />

Pigmentation (

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