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Drug Eruption and Interactions - PHARMACEUTICAL REVIEW

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118 CHLORMEZANONE<br />

Other<br />

Death<br />

CHLOROQUINE<br />

Trade names: Aralen (Sanofi-Aventis); Avloclor; Chlorquin;<br />

Emquin; Heliopar; Lagaquin; Malarivon<br />

Indications: Malaria, rheumatoid arthritis, lupus erythematosus<br />

Category: Antimalarial; Antiprotozoal; Disease-modifying<br />

antirheumatic<br />

Half-life: 3–5 days<br />

Clinically important, potentially hazardous interactions<br />

with: acitretin, antacids, cholestyramine, dapsone, furazolidone,<br />

hydroxychloroquine, methotrexate, methoxsalen, penicillamine,<br />

sulfonamides<br />

Reactions<br />

Skin<br />

Acute generalized exanthematous pustulosis (AGEP)<br />

(1998): Janier M+, Dermatology 196, 271<br />

Angioedema (

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