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Drug Eruption and Interactions - PHARMACEUTICAL REVIEW

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Porphyria variegata<br />

(2001): Grieco A+, Eur J Gastroenterol Hepatol 13(8), 973<br />

Pseudolymphoma<br />

(2006): Alvarez-Ruiz S+, Actas Dermosifiliogr 97(1), 43<br />

(2001): Cogrel O+, Br J Dermatol 144(6), 1235<br />

(2001): Mir<strong>and</strong>a-Romero A+, Cutis 67(1), 47<br />

(1999): Saeki H+, JDermatol26, 329<br />

(1998): d’Incan M+, Ann Dermatol Venereol 125, 52<br />

(1998): Nathan D+, JAmAcadDermatol38, 806<br />

(1997): Kim ST+, Korea, American Academy of Dermatology<br />

Meeting (SF), Poster #82<br />

(1997): Paramesh H+, Indian Pediatr 34, 829<br />

(1996): Callot V+, Arch Dermatol 132, 1315<br />

(1995): Magro CM+, JAmAcadDermatol32, 419<br />

(1993): Rondas AA+, Ned Tijdschr Geneeskd (Dutch) 137, 1258<br />

(1993): Sigal M+, Ann Dermatol Venereol (French) 120, 175<br />

(1991): Rijlaarsdam U+, JAmAcadDermatol24(2), 216<br />

(1990): Sinnige HAM+, J Intern Med 227, 355<br />

(1986): Yates P+, J Clin Pathol 39, 1224<br />

(1984): Shuttleworth D+, Clin Exp Dermatol 9, 424<br />

Rhabdomyolysis<br />

(1992): Zele I+, Minerva Med 83(12), 847<br />

Serum sickness<br />

(1993): Igarashi M+, Int Arch Allergy Immunol 100, 378<br />

Thrombophlebitis<br />

CARBENICILLIN<br />

Trade names: Carbecin; Carbelin; Geocillin (Pfizer); Geopen;<br />

Pyopen<br />

Indications: Urinary tract infections<br />

Category: Antibiotic, penicillin<br />

Half-life: 1.0–1.5 hours<br />

Clinically important, potentially hazardous interactions<br />

with: anticoagulants, ceftobiprole, cyclosporine, demeclocycline,<br />

doxycycline, gentamicin, imipenem/cilastatin, methotrexate,<br />

minocycline, oxytetracycline, tetracycline<br />

Reactions<br />

Skin<br />

Allergic reactions (sic)<br />

(1994): Pleasants RA+, Chest 106, 1124 (in patients with cystic<br />

fibrosis)<br />

Angioedema<br />

Bullous dermatitis<br />

Edema<br />

Erythema multiforme<br />

Erythema nodosum<br />

Exanthems<br />

Exfoliative dermatitis<br />

Hematomas<br />

Hemorrhage<br />

Jarisch–Herxheimer reaction<br />

Pruritus<br />

Purpura<br />

Rash (sic) (

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