Drug Eruption and Interactions - PHARMACEUTICAL REVIEW

84 CAFFEINE
Burning (feet)
(1982): Young JJ+, Drug Intell Clin Pharm 16(10), 779
Exfoliative dermatitis
Facial edema
Pemphigus
(1990): Brenner S+, Acta Derm Venereol 70(4), 357
(+paracetamol, chlorpheniramine, phenylephrine)
Pruritus
Purpura
Rash (sic)
Rosacea
(2001): Goldman D, JAmAcadDermatol44(6), 995
Urticaria
(2002): Fernandez-Nieto M+, Allergy 57(10), 967 (cola drink)
(1999): Kubota Y+, Eur J Dermatol 9(7), 559 (+aspirin)
(1993): Caballero T+, J Investig Allergol Clin Immunol 3(3), 160
(1991): Quirce Gancedo+, J Allergy Clin Immunol 88(4), 680
(1988): Pola J+, Ann Allergy 60(3), 207
Xanthoderma
Mucosal
Xerostomia
(2002): Boozer CN+, IntJObesRelatMetabDisord26(5), 593
(with ephedra)
Other
Anaphylactoid reactions/Anaphylaxis
(2003): Infante S+, Allergy 58(7), 681
(1999): Kubota Y+, Eur J Dermatol 9(7), 559 (+aspirin)
(1983): Przybilla B+, Hautarzt (German) 34(2), 73
Chills
(1988): Mattila M+, Int Clin Psychopharmacol 3(3), 215
Death (from abuse/overdose)
(2003): Kanstrup MH+, Ugeskr Laeger 165(3), 239 (with
ephedrine)
(2001): Ahrendt DM, Am Fam Physician 63(5), 913
(2000): Le Coz, Presse Med (French) 29(1), 33
(2000): Tanskanen A+, Eur J Epidemiol 16(9), 789
(2000): Zivkovic R, Acta Med Croatica 54(1), 33
(1999): Zahn KA+, J Emerg Med 17(2), 289 (herbal ecstasy)
(1998): Ferslew KE+, JForensicSci43(5), 1082 (+clozapine,
fluoxetine)
(1997): Shum S+, Vet Hum Toxicol 39(4), 228
(1990): Lake CR+, Int J Obes 14(7), 575
(+phenylpropanolamine)
(1989): Mrvos RM+, Vet Hum Toxicol 31(6), 571 (diet pills)
(1986): Hanzlick R+, J Anal Toxicol 10(3), 126
(1985): Garriott JC+, J Anal Toxicol 9(3), 141
(1985): Winek CL+, Forensic Sci Int 29(3–4), 207
(1985): Zimmerman PM+, Ann Emerg Med 14(12), 1227
(1981): Bryant J, Arch Pathol Lab Med 105, 685
(1980): McGee MB, JForensicSci25(1), 29
Hypersensitivity
(2002): Hinrichs R+, Allergy 57(9), 859
Rhabdomyolysis
(1999): Kamijo Y+, Vet Hum Toxicol 41(6), 381 (oolong tea)
(1998): Kasamatsu Y+, Intern Med 37(2), 169 (cold remedy)
(1995): Dawson JK+, J Accid Emerg Med 12(1), 49 (+ephedrine,
theophylline)
(1991): Michaelis HC+, J Toxicol Clin Toxicol 29(4), 521
(overdose, +acetaminophen, phenazone)
(1989): Wrenn KD+, Ann Emerg Med 18(1), 94 (overdose)
CALCITONIN
Trade names: Calcimar (Sanofi-Aventis); Caltine; Cibacalcine;
Clasynar; Miacalcic; Miacalcin (Novartis)
Indications: Paget’s disease of bone
Category: Parathyroid hormone antagonist
Half-life: 70–90 minutes
Reactions
Skin
Allergic reactions (sic)
(2001): Rodriguez A+, Allergy 56(8), 801
Exanthems
Granuloma annulare
(1993): Goihman YM, Int J Dermatol 32, 150
Palmar–plantar tenderness
Peripheral edema
Pruritus
Rash (sic) (10%)
Injection-site pain
(1988): Warrell RP+, AnnInternMed108, 669 (62%)
CALCIUM HYDROXYLAPATITE
Trade name: Radiesse (BioForm) (Radiance FM)
Indications: Correction of facial wrinkles and folds
Category: Dermal filler
Half-life: N/A
Clinically important, potentially hazardous interactions
with: anticoagulants, antiplatelet drugs, aspirin
Reactions
Skin
Edema
(2006): Silvers SL+, Plast Reconstr Surg 118(3 Suppl), 34S
Erythema
(2006): Silvers SL+, Plast Reconstr Surg 118(3 Suppl), 34S
Hematomas
(2006): Jacovella PF+, Plast Reconstr Surg 118(3 Suppl), 15S
Nodular eruption
(2006): Jansen DA+, Plast Reconstr Surg 118(3 Suppl), 22S
Pruritus
(2006): Silvers SL+, Plast Reconstr Surg 118(3 Suppl), 34S
Other
Pain
(2006): Silvers SL+, Plast Reconstr Surg 118(3 Suppl), 34S