Drug Eruption and Interactions - PHARMACEUTICAL REVIEW

32 AMOXICILLIN
(2000): Blumenthal HL, Beachwood, OH (personal case)
(observation)
(1998): Minguez MA+, Allergol Immunopathol (Madr) (Spanish)
26, 43
(1997): Delpre G+, Dig Dis Sci 42, 728
(1997): Thaler D, Monona, WI (from internet) (observation)
(1995): Litt JZ, Beachwood, OH (personal case) (observation)
(1994): Vega JM+, Allergy 49, 317
(1990): Fraj J+, Clin Exp Allergy 20, 121
(1989): Battegay M+, Lancet 2, 1100
(1989): Chopra R+, Can Med Assoc J 140, 921 (in children)
(1985): Goolamali SK, Postgrad Med J 61, 925
Vasculitis
(1999): Garcia-Porrua C+, J Rheumatol 26, 1942
Vesiculation
Mucosal
Glossitis
Glossodynia
Oral candidiasis
Stomatitis
(1996): Drouet M+, Allerg Immunol Paris (French) 28, 311
Stomatodynia
Tongue black
Vaginitis (1%)
(2004): Leophonte P+, Respir Med 98(8), 708
(1996): Drouet M+, Allerg Immunol Paris (French) 28, 311
Xerostomia
(1995): Hautekeete ML+, JHepatol22(1), 71
Eyes
Visual hallucinations
(1996): Stell IM+, Br J Clin Pract 50(5), 279
Other
Anaphylactoid reactions/Anaphylaxis
(2007): Del Furia F+, Int J Cardiol 117(1), e37
(2003): Gei AF+, Obstet Gynecol 102(6), 1332
(2001): Torres MJ+, Allergy 56(9), 850
(1999): Salgado Fernandez J+, Rev Esp Cardiol (Spanish) 52, 622
(1998): Rich MW, Tex Heart Inst J 25, 194
(1994): Vega JM+, Allergy 49, 317
(1993): van der Klauw MM+, Br J Clin Pharmacol 35, 400
(1990): Fraj J+, Clin Exp Allergy 20, 121
(1988): Blanca M+, Allergy 43, 508
Anticonvulsant hypersensitivity syndrome
(2006): Gaig P+, J Investig Allergol Clin Immunol 16(5), 321
Hepatotoxicity
(2007): Cundiff J+, Am J Otolaryngol 28(1), 28
(2006): Andrade RJ+, Hepatology 44(6), 1581
(2006): Lucena MI+, Hepatology 44(4), 850
(2005): Fontana RJ+, Dig Dis Sci 50(10), 1785
(2005): Solano Remirez M+, An Med Interna 22(7), 350
(2002): Jordan T+, Gastroenterol Hepatol 25(4), 240
(2001): Ersoz G+, J Clin Pharm Ther 26(3), 225
(1998): Julve R+, Gastroenterol Hepatol 21(2), 92
(1998): Nathani MG+, Am J Gastroenterol 93(8), 1363
(1995): Hautekeete ML+, JHepatol22(1), 71
Hypersensitivity
(2000): da Fonseca MA, Pediatr Dent 22(5), 401
(1995): Mokry C, NEnglJMed333, 1151
(1993): Romano A+, Contact Dermatitis 28, 190
(1989): Kennedy C+, Contact Dermatitis 20, 313
Injection-site pain
Nephrotoxicity
(2006): Huang SF+, Zhongguo Dang Dai Er Ke Za Zhi 28(3), 254
Rhabdomyolysis
(2004): Bhatia V, JPostgradMed50(3), 234 (with simvastatin)
Serum sickness (1–10%)
(1995): Martin J+, NZMedJ108, 123
(1992): Stricker BH+, J Clin Epidemiol 45, 1177
(1990): Heckbert SR+, Am J Epidemiol 132, 336
(1989): Chopra R+, Can Med Assoc J 140, 921 (in children)
(1988): Platt R+, JInfectDis158, 474
AMPHOTERICIN B
Trade names: Abelcet (Wyeth); AmBisome (Astellas); Ampho-
Moronal; Amphocin (Pfizer); Fungilin; Fungizone
Indications: Potentially life-threatening fungal infections
Category: Antimycobacterial
Half-life: initial: 15–48 hours; terminal: 15 days
Clinically important, potentially hazardous interactions
with: adefovir, aminoglycosides, astemizole, cephalothin,
cidofovir, cyclosporine, digoxin, fluconazole, flucytosine,
ganciclovir, griseofulvin, hydrocortisone, itraconazole,
ketoconazole, probenecid, terbinafine
Reactions
Skin
Acute generalized exanthematous pustulosis (AGEP)
(2007): Heinemann C+, JAmAcad57(2), S61
Angioedema
Burning (from topical)
Dermatitis
Diaphoresis
Erythema
Erythema multiforme
(2006): Hernandez-Salazar A+, Arch Med Res 37(7), 899
Exanthems (