Protocol Title : A Randomised, open labelled study in anti ... - EME
Protocol Title : A Randomised, open labelled study in anti ... - EME
Protocol Title : A Randomised, open labelled study in anti ... - EME
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components, the erosion score and jo<strong>in</strong>t space narrow<strong>in</strong>g score. Inhibition of jo<strong>in</strong>t structural<br />
damage was shown with significantly less radiographic progression <strong>in</strong> patients receiv<strong>in</strong>g<br />
tocilizumab compared to control. In the <strong>open</strong>-label extension of this <strong>study</strong> the <strong>in</strong>hibition of<br />
progression of structural jo<strong>in</strong>t damage <strong>in</strong> tocilizumab plus MTX-treated patients was ma<strong>in</strong>ta<strong>in</strong>ed <strong>in</strong><br />
the second year of treatment. The mean change from basel<strong>in</strong>e at week 104 <strong>in</strong> total Sharp-Genant<br />
score was significantly lower for patients randomised to tocilizumab plus MTX (p