Dietary Supplements in Myelodysplastic Syndromes

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Literature Review of antioxidant supplementation on chemotherapeutic toxicity • 33 of 965 articles: RCT, met criteria, N= 2,446 • 24/33 reported ↓ toxicities from concurrent use of antioxidants with chemotherapy. • 9 reported no difference in toxicities • 1 (vitamin A) reported a significant increase in toxicity in the antioxidant group • 5 reported antioxidant group had more full dose or less dose-reduction than control groups Into J Cancer. 2008 Sep 15;123(6):1227-39
Supplement Summary • Resveratrol 500-1000 mg/d • Indole-3-Carbinol 300-400 mg/d • Turmeric (black pepper) 300-1000 mg/d • EGCG 500-750 mg/d • DIM 300 mg/d • Vit D 1000 IU/d • PEITC ? • Fish Oil (sum of DHA+EPA) 1000 mg/d
Page 1 and 2: Dietary Supplements in Myelodysplas
Page 3 and 4: Objectives • To know the Definiti
Page 5 and 6: Integrative Medicine Consultation
Page 7 and 8: Supplement Information Resource htt
Page 10: Mediterranean/Anti inflammatory Die
Page 14 and 15: Molecular targets of chemopreventiv
Page 16 and 17: Supplements Resveratrol- 500- 1000
Page 18: Supplements, Actions Curcumin- Turm
Page 21 and 22: Epigenetic roles of nutrition
Page 23 and 24: Indole 3 Carbinol (I3C) 300 mg/d 3,
Page 25 and 26: Cruciferous Vegetables
Page 27 and 28: Supplement, Actions Genistein- Soyb
Page 29 and 30: Gingerol and Curcumin in low risk m
Page 31 and 32: Green Tea and Bortezomib BAD! • G
Page 33: Are Antioxidants counterproductive
Page 37: Bibliography • Mellibovsky I. et

Dietary Supplements in Myelodysplastic Syndromes

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