Dietary Supplements in Myelodysplastic Syndromes
Dietary Supplements in Myelodysplastic Syndromes
Dietary Supplements in Myelodysplastic Syndromes
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Vitam<strong>in</strong> D treatment <strong>in</strong> MDS<br />
• 19 pts. Responders- either granulocyte or<br />
platelet count ↑ 50%, Hgb ↑ 1·5 g/dl, Transfusion<br />
needs ↓ 50%.<br />
• Calcifediol- 5 pts, Calcitriol- 14 pts<br />
• Calcifediol- 1/5 rspnd, 3/5 nonrspnd, 1/5 prog.<br />
• Calcitriol- 10/14 rspnd, (2 major) 4/14nonrspnd<br />
• Basel<strong>in</strong>e Vit D levels not related to response.<br />
Conclusion: “Vit D3 could <strong>in</strong>duce a longstand<strong>in</strong>g<br />
response <strong>in</strong> some low-<strong>in</strong>termediate risk MDS<br />
patients without <strong>in</strong>duc<strong>in</strong>g hypercalcemia”.<br />
Brit J of Haematology, 1998, 100, 516–520
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