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Dietary Supplements in Myelodysplastic Syndromes

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<strong>Supplements</strong><br />

Resveratrol- 500- 1000 mg/d<br />

A polyphenol found <strong>in</strong> grape sk<strong>in</strong>s. Grapes and<br />

grape juice, grape seed extract.<br />

Inhibits proliferation of cancer cells via<br />

apoptosis and also by exert<strong>in</strong>g anti- estrogen<br />

effects<br />

Sales have skyrocketed, strong use <strong>in</strong> cancer<br />

patients and elderly<br />

Strong <strong>in</strong>hibitor of CYP2D6 and CYP2D9.<br />

Aggarwal, et al. Anticancer Res. 2004;24:2783‐2840<br />

Banerjee, et al. Cancer Res. 2002;62(17):4945‐4954

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