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Internal Medicine Board Review - DiscWrite CD Promotions

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Multiple Myeloma<br />

• Look for a patient with anemia, hypercalcemia<br />

and renal insufficiency<br />

• Lytic bone lesions, vertebral fracture, or back<br />

pain increased at night g<br />

• Low anion gap*<br />

• How high is the level of serum alkaline<br />

phosphatase?<br />

• Normal<br />

• Diagnosis:<br />

– Serum M protein > 3 g/dL<br />

– X ray of the skeleton* (which is better bone scan or X ray)<br />

– Plasma cells > 10% in the bone marrow

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