Internal Medicine Board Review - DiscWrite CD Promotions

CLL – on the Boards
• Look for a stable CLL patient with HB of 12 g/dL
who developed significant drop of HB to 8 g/dL
with increased bilirubin and LDH within few
weeks
• Think of Evans’ syndrome - immune reaction
rather than progressive CLL – Do not start
chemotherapy*
• Ri Richter’s h ’ transformation f i - 3 -10% 10% of f patients i
with CLL may transform into a large cell
lymphoma → a very poor prognosis