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Internal Medicine Board Review - DiscWrite CD Promotions

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Myelodysplastic syndromes<br />

(MDS) Look for:<br />

• AAn older ld patient ti t with ith progressive i anemia i<br />

(low reticulocyte count), or cytopenia in 2<br />

or more cell ll li lines<br />

• Blast > 5% in the bone marrow<br />

• Cytogenic abnormality (chromosomes<br />

3,5,7,8 and 17)<br />

What is the chromosomal Deletion at 5q abnormality with the best<br />

prognosis?<br />

Treatment blood transfusion, transfusion erythropoietin and<br />

MBT if < 60 years

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