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Internal Medicine Board Review - DiscWrite CD Promotions

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Polycythemia vera (PCV)<br />

A62 A 62-year-old ld male l with ith no medical di l hi history t<br />

complaining of pruritus after bathing- Has<br />

splenomegaly and his Hg 19 19.5 5 g/dL g/dL, O2 sat<br />

92% and normal erythropoietin level<br />

↑leukocyte alkaline phosphatase, Fe deficiency, and ↑ B12 level<br />

(due to increased binding protein transcobalamin I)<br />

Treat with ASA to all the patients –phlebotomy (HCT 70 year, h/o thrombosis, platelet > 400,000/µL)<br />

JAK 2 gene g<br />

occurs in almost 80% of PCV patients

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