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Cervical Cancer

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Patients with stage IVB,<br />

recurrent, or persistent<br />

squamous cell cervical<br />

cancer<br />

(N = 264*)<br />

GOG 169<br />

Quality of life (QoL) and tumor<br />

measured after each cycle<br />

Cisplatin (50 mg/m 2 )<br />

Day 1 of a 21-day cycle<br />

6 cycles total<br />

N = 134<br />

Cisplatin (50 mg/m 2 )/Paclitaxel (135 mg/m 2 ) **<br />

Day 1 of a 21-day cycle<br />

6 cycles total<br />

N = 130<br />

*280 patients enrolled; 16 ineligible (8 from each arm) N = 264 for intent-to-treat analysis<br />

**Paclitaxel given as a 24-hour infusion followed immediately by cisplatin.<br />

Moore DH, et al. J Clin Oncol. 2004;22:3113-3119.

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