Cervical Cancer
Cervical Cancer
Cervical Cancer
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Patients with stage IVB,<br />
recurrent, or persistent<br />
squamous cell cervical<br />
cancer<br />
(N = 264*)<br />
GOG 169<br />
Quality of life (QoL) and tumor<br />
measured after each cycle<br />
Cisplatin (50 mg/m 2 )<br />
Day 1 of a 21-day cycle<br />
6 cycles total<br />
N = 134<br />
Cisplatin (50 mg/m 2 )/Paclitaxel (135 mg/m 2 ) **<br />
Day 1 of a 21-day cycle<br />
6 cycles total<br />
N = 130<br />
*280 patients enrolled; 16 ineligible (8 from each arm) N = 264 for intent-to-treat analysis<br />
**Paclitaxel given as a 24-hour infusion followed immediately by cisplatin.<br />
Moore DH, et al. J Clin Oncol. 2004;22:3113-3119.