CURRICULUM VITAE Of Owen Abraham Obel - UT Southwestern
CURRICULUM VITAE Of Owen Abraham Obel - UT Southwestern
CURRICULUM VITAE Of Owen Abraham Obel - UT Southwestern
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<strong>CURRICULUM</strong> <strong>VITAE</strong><br />
<strong>Of</strong><br />
<strong>Owen</strong> <strong>Abraham</strong> <strong>Obel</strong>
Name <strong>Owen</strong> A. <strong>Obel</strong><br />
Address 4429 Edmondson Avenue, Dallas,Texas, 75205 USA<br />
Telephone (+1) 214 824 5446 (home)<br />
(+1) 469 831 8950 (cell)<br />
E mail owen.obel@utsouthwestern.edu<br />
Date of Birth 22 May 1962, Johannesburg, South Africa<br />
Nationality South African, UK<br />
US Permanent Resident<br />
Licensure Massachusetts (Full)<br />
Texas (Full)<br />
United Kingdom (Internal Medicine, Cardiology)<br />
South Africa (Internal Medicine, Cardiology)<br />
General Education King Edward VII and Redhill School<br />
Johannesburg, South Africa 1974 - 1980<br />
Medical Education University of Witwatersrand 1981 - 1986<br />
Johannesburg, South Africa<br />
Qualifications MB BCh (MD) Dec 1986<br />
(Honors in Medicine and Pediatrics)<br />
Member of Royal College of Physicians (UK)<br />
Nov 1993<br />
UK - Board certified equivalent (Internal Medicine and<br />
Cardiology)<br />
South Africa – Board certified equivalent (Internal<br />
Medicine and Cardiology)<br />
Thesis University of London 2011 (Doctor of Medicine)<br />
Supervisor: Professor AJ Camm<br />
Title: Thromboembolism in Atrial Fibrillation:<br />
Hemodynamic and Haematologic Mechanisms<br />
2
Current Position<br />
November 2004 - Present<br />
Director of Pacing and Electrophysiology,<br />
Dallas VA Medical Center<br />
Assistant Professor in Medicine and Cardiology<br />
Director of Education - EP Fellowship Program,<br />
<strong>UT</strong> <strong>Southwestern</strong> Medical Center, Dallas, Texas<br />
- Director of fully equipped invasive EP lab at<br />
DVAMC (biplane lab with all standard<br />
equipment including CARTO, ESI and<br />
intracardiac echo) with ± 700 cases performed<br />
annually (approximately 400 devices; 200<br />
standard ablations, 70 AF ablations, 20 VT<br />
ablations/year)<br />
- Responsible for running of EP and Pacing<br />
Service at DVAMC<br />
- Responsible for compiling and running<br />
educational curriculum training of 4 ACGME–<br />
accredited EP Fellows at <strong>UT</strong> <strong>Southwestern</strong>, 2<br />
of whom are full-time at DVAMC<br />
Cardiological Training<br />
EP Fellowship<br />
July 2002 –June 2004 Clinical Fellow in Cardiac Pacing and<br />
Electrophysiology<br />
Cardiac Arrhythmia Service<br />
Massachusetts General Hospital, Boston, USA<br />
Supervisor: Dr Jeremy Ruskin<br />
Cardiology Fellowship St Georges, Hospital, London (and affiliated hospitals)<br />
Oct ’98 – June 2002 Specialist Registrar in Cardiology<br />
Supervisors: Prof AJ Camm; Dr E Rowland<br />
Oct ’2000 – Oct 2001 Specialist Registrar in Cardiology<br />
Sussex Cardiac Centre – Royal Sussex County<br />
Hospital, Brighton, UK<br />
Supervisor: Dr S O ‘Nunain<br />
Oct ’99 – Oct 2000 Specialist Registrar in Cardiology<br />
Mayday University Hospital, London, UK<br />
Supervisor: Dr S Joseph<br />
3
Oct ’98 – Oct ’99 Specialist Registrar in Cardiology<br />
Worthing Hospital, UK<br />
Supervisor: Dr M Signy<br />
Feb ’96 – Oct ’98 Research Fellow in Cardiology, Electrophysiology<br />
St George’s Hospital, London, UK<br />
Supervisor: Professor AJ Camm<br />
Skills<br />
Research Interests<br />
Trained and experienced in all aspects of invasive<br />
electrophysiology.<br />
Trained and experienced in cardiac arrhythmia<br />
ablation including AF and VT ablation (including<br />
epicardial ablation) at 1 st operator level including<br />
frequent current use of electroanatomical mapping<br />
techniques (CARTO and ESI) and intracardiac echo.<br />
Trained and experienced in pacemaker and ICD<br />
implantation and interpretation having performed well<br />
over 1000 such procedures at 1 st operator level.<br />
Trained and experienced in complex and biventricular<br />
device implantation, device revision, and device<br />
upgrades, tunnelling etc, at 1 st operator level.<br />
Trained in transthoracic echocardiography, basic<br />
transesophageal echocardiography, extensive<br />
diagnostic coronary angiography.<br />
Main current research interest: Effect of AV node<br />
ablation and biventricular pacing for refractory AF and<br />
heart failure on atrial electrical remodelling (recently<br />
awarded VISN 17 grant -$100 000).<br />
PI in Dallas for Impulse Dynamics – a study on<br />
Cardiac Contractility Modulation in Heart Failure (FIX<br />
HF 5)<br />
Publications<br />
Camm AJ, <strong>Obel</strong> OA. Epidemiology and mechanism of atrial fibrillation and atrial<br />
flutter. American Journal of Cardiology 1996; 78(8A):3-11<br />
<strong>Obel</strong> OA, Camm AJ. Supraventricular tachycardia. ECG diagnosis and anatomy.<br />
European Heart Journal 1997; 18 Suppl C:C2-11<br />
<strong>Obel</strong> OA, Camm AJ. Accessory pathway reciprocating tachycardia. European<br />
Heart Journal 1998; 19 Suppl E: E13-E24<br />
4
<strong>Obel</strong> OA, Camm AJ. The use of drugs for cardioversion of recent onset atrial<br />
fibrillation and flutter: focus on ibutilide. Drugs & Aging 1998; 12 (6): 461-76<br />
<strong>Obel</strong> OA, Rowland ER. Characteristics and differential diagnosis of arrhythmias.<br />
Chapter in Arrhythmogenic Right Ventricular Cardiomyopathy/Dysplasia. Nava A,<br />
Rossi L, Thiene G (Eds). pp197-209, Elselvier, Amsterdam 1997<br />
<strong>Obel</strong> OA, Camm AJ. Alcohol and the heart. Alcoholism 1998; 17(3): 1-2<br />
<strong>Obel</strong> OA, Camm AJ. Supraventricular Tachycardia. Chapter in Cardiology.<br />
Bayes de Luna A, Brochier M, Dienstl F, Jezek V, Mortensen SA, Poole-Wilson<br />
PA, Braunwald E (Eds). pp191-200, McGraw-Hill, London 1999<br />
<strong>Obel</strong> OA, Camm AJ. Atrioventricular nodal re-entry: prevalence, presentation,<br />
management, and new strategies for intervention in the context of aviation.<br />
European Heart Journal 1999 Suppl D: D98-D104<br />
<strong>Obel</strong> OA, Ward DEW. Advances in Implantable Cardioverter-Defibrillators. Asian<br />
Journal of Cardiology 1999<br />
Gallagher MM, <strong>Obel</strong> OA, Camm AJ. Tachycardia-induced atrial myopathy: an<br />
important mechanism in the pathophysiology of atrial fibrillation? Journal of<br />
Cardiovascular Electrophysiology 1997; 8(9):1065-74<br />
Hnatkova K, <strong>Obel</strong> OA, Camm AJ, Malik M. Technical Advances in Signal-<br />
Averaged Electrocardiography. Cardiac Electrophysiology Review 1997; 1(3):<br />
317-320<br />
Price A. <strong>Obel</strong> OA. Cresswell J. Catch I. Rutter S. Barik S. Heller SR. Weetman<br />
AP. Comparison of thyroid function in pregnant and non-pregnant Asian and<br />
western Caucasian women. Clinica Chimica Acta. 308(1-2):91-8, 2001 Jun<br />
Al-Saady NM, <strong>Obel</strong> OA, Camm AJ. The Left Atrial Appendage: structure,<br />
function, and role in thromboembolism. Heart 1999; 82: 547-555<br />
<strong>Obel</strong> OA. Revisiting established medical options - antiarrhythmic drugs and betablocker<br />
combinations. Resuscitation 2000: 45(3):S7-S10<br />
<strong>Obel</strong> OA, Coltart DJ, Signy M. Balloon Pulmonary Valvuloplasty in Carcinoid<br />
Syndrome. Heart 2000: 83: e2000<br />
<strong>Obel</strong> OA, Camm AJ. Economic Aspects of Implantable-Cardioverter-Defibrillator<br />
Therapy. Chapter in Fighting Sudden Cardiac Death. Aliot E, Clementy J,<br />
Prystowsky E [Eds]. pp 671-688, Futura, Armonk, New York 2000<br />
5
Gallagher MM. Hennessy BJ. Edvardsson N. Hart CM. Shannon MS. <strong>Obel</strong> OA.<br />
Al-Saady NM. Camm AJ. Embolic complications of direct current cardioversion of<br />
atrial arrhythmias: association with low intensity of anticoagulation at the time of<br />
cardioversion. Journal of the American College of Cardiology. 40: 926-33; 2002<br />
<strong>Obel</strong> OA, Davidson C. Arrhythmias in an Athlete: The Effect of De-Training.<br />
Postgraduate Medical Journal; 81:62-64 2005<br />
<strong>Obel</strong> OA, Mansour M, Picard M, Ruskin JR, Keane D Persistence of Septal<br />
Defects After Transeptal Puncture for Pulmonary Vein Isolation Procedures<br />
PACE; 27:1411-1414, 2004<br />
<strong>Obel</strong> OA, Luddington L, Maarouf N, Aytemir K, Ekwall C, Malik M, Camm AJ.<br />
The Effects of Ventricular Rate and Regularity on the Velocity and Magnitude of<br />
Left Atrial Appendage Flow in Atrial Fibrillation. Heart 2005; 91: 764-768<br />
<strong>Obel</strong> OA, d’Avila A, Saad E, Neuzil P, Ruskin R, Reddy V. Ablation of Left<br />
Ventricular Epicardial Outflow Tract Tachycardia from the Distal Great Cardiac<br />
Vein. J Am Coll Cardiol 48:1813-17, 2006<br />
Nesbitt WH, Lampe C, Lustgarten D, <strong>Obel</strong> OA. Supraventricular Tachycardia<br />
with Two VA Intervals: What is the Mechanism? PACE; 30(2):253-5 2007<br />
Chen J, Naseem RH, <strong>Obel</strong> OA, Joglar J. Habitual Cocaine Use Is Associated<br />
with High Defibrillation Threshold During ICD Implantation. Journal of<br />
Cardiovascular Electrophysiology, 18: 722-725, 2007<br />
Brilakis ES, Collins LJ, <strong>Obel</strong> OA, Banerjee S Mechanical valve dysfunction after<br />
percutaneous perimitral leak closure: salvage by percutaneous occluder retrieval.<br />
Catheter Cardiovasc Interv. 75(6):876-81, 2010<br />
Daniels J, Saunders J, Parvethanani S, Byrd A, Joglar J, <strong>Obel</strong> OA.<br />
ICD Electrocardiographic Findings, Device Therapies, and Comorbidities in<br />
Octogenarian Implantable Defibrillator Recipients. Journal of Cardiovascular<br />
Electrophysiology, 21: 236-241, 2010<br />
Kadish A, Nademanee K, Volosin K, Krueger S, Neelagaru S, Raval N, <strong>Obel</strong> O,<br />
Weiner S, Wish M, Carson P, Ellenbogen K, Bourge R, Parides M, Chiacchierini<br />
RP, Goldsmith R, Goldstein S, Mika Y, Burkhoff D, <strong>Abraham</strong> WT. A randomized<br />
controlled trial evaluating the safety and efficacy of cardiac contractility<br />
modulation in advanced heart failure. Am Heart J.161(2):329-337,2011<br />
Daniels JD, Sun S, Zafereo J, Minhajuddin A, Nguyen C, <strong>Obel</strong> O, Wu R, Joglar<br />
JA Preventing shoulder pain after cardiac rhythm management device<br />
implantation: a randomized, controlled study. Pacing Clin Electrophysiol. 2011<br />
Jun;34(6):672-8.<br />
6
Brilakis ES, Lichtenwalter C, Abdel-karim AR, de Lemos JA, <strong>Obel</strong> O, Addo T,<br />
Roesle M, Haagen D, Rangan BV, Saeed B, Bissett JK, Sachdeva R, Voudris<br />
VV, Karyofillis P, Kar B, Rossen J, Fasseas P, Berger P, Banerjee S. Continued<br />
benefit from paclitaxel-eluting compared with bare-metal stent implantation in<br />
saphenous vein graft lesions during long-term follow-up of the SOS (Stenting of<br />
Saphenous Vein Grafts) trial. JACC Cardiovasc Interv. 2011 Feb;4(2):176-82.<br />
<strong>Abraham</strong> WT, Nademanee K, Volosin K, Krueger S, Neelagaru S, Raval N, <strong>Obel</strong><br />
O, Weiner S, Wish M, Carson P, Ellenbogen K, Bourge R, Parides M,<br />
Chiacchierini RP, Goldsmith R, Goldstein S, Mika Y, Burkhoff D, Kadish A; FIX-<br />
HF-5 Investigators and Coordinators. Subgroup analysis of a randomized<br />
controlled trial evaluating the safety and efficacy of cardiac contractility<br />
modulation in advanced heart failure. J Card Fail. 2011 Sep;17(9):710-7.<br />
<strong>Owen</strong>s A, Heinzman K, <strong>Obel</strong> O. Anti-tachycardia pacing as both therapy and<br />
diagnostic tool. What is the diagnosis? Heart Rhythm. 2011 May 25. [Epub ahead<br />
of print]<br />
Lo MY, <strong>Obel</strong> O. Maximizing Cardiac Resynchronization Therapy in Patients With<br />
Atrial Fibrillation. Journal of Innovations in Cardiac Rhythm Management. 2011<br />
(2) 584-593<br />
Letters<br />
<strong>Obel</strong> OA. Cardiological examinations. Journal of the Royal College of Physicians<br />
of London 1997; 31(6):704-5<br />
Abstracts<br />
<strong>Obel</strong> OA, Al-Saady N, Fredericks S, Gallagher M, Waktare J, Camm AJ. Patients<br />
With Non-Valvular Atrial Fibrillation Have Evidence of Thrombin Generation But<br />
Not Endothelial Activation. Journal of the American College of Cardiology 1998;<br />
31 (2A): 332A<br />
<strong>Obel</strong> OA, Treasure T, Murday A, Smith J, Gaer J, Camm AJ. The Effects of Brief<br />
Periods of Acute Atrial Fibrillation on Left Atrial Mechanical Function and<br />
Activation of Coagulation. PACE; 1998, 21 (4) II: 897<br />
<strong>Obel</strong> OA, Treasure T, Murday A, Smith J, Gaer J, Camm AJ. The Effects of<br />
Post-Operative Atrial Fibrillation on Left Atrial Mechanical Function and Activation<br />
of Coagulation. European Heart Journal; 1998, 19 (Suppl): 96<br />
<strong>Obel</strong> OA, Al-Saady N, Luddington L, Murday A, Treasure T, Camm AJ.<br />
Hypercoagulability of Left Atrial Appendage Blood From Patients With Atrial<br />
Fibrillation. European Heart Journal; 1998, 19 (Suppl): 460<br />
7
<strong>Obel</strong> OA, Al-Saady N, Luddington L, Murday A, Treasure T, Camm AJ. Regional<br />
Intra-cardiac Variability of Pre-thrombotic Markers in Patients with Non-valvular<br />
Atrial Fibrillation. Circulation; 1998, 17 (Suppl): 704<br />
<strong>Obel</strong> OA, Aytemir K, Luddington L, Maarouf N, Ekwall C, Malik M, and Camm<br />
AJ; The Efffects of Ventricular Rate and Rhythm on the Velocity and Magnitude<br />
of Left Atrial Appendage Flow in Patients With Atrial Fibrillation. PACE; 1999, 22<br />
(4), 710<br />
<strong>Obel</strong> OA, Aytemir K, Luddington L, Maarouf N, Ekwall C, Malik M, and Camm<br />
AJ; The Relative Effects of Ventricular Rate and Rhythm on Ejection Fraction in<br />
Patients With Atrial Fibrillation, PACE; 1999, 22 (4), 710<br />
<strong>Obel</strong> OA, Aytemir K, Luddington L, Maarouf N, Ekwall C, Malik M, and Camm<br />
AJ; The Efffects of Ventricular Rate and Rhythm on the Velocity and Magnitude<br />
of Left Atrial Appendage Flow in Patients With Atrial Fibrillation, PACE 1999, 22<br />
(4), 842<br />
Gallagher MM, Hart CM, Shannon MS, <strong>Obel</strong> OA, Al-Saady N, Camm AJ.<br />
Embolic Complications of Direct Current Cardioversion of Atrial Arrhythmias.<br />
PACE; 1998, 21 (4) II: 953<br />
M.M. Gallagher, C.M. Hart, M.S Shannon, <strong>Obel</strong> OA, N.M. Al-Saady, A.J. Camm.<br />
Safety of Direct Current Conversion of Atrial Arrhythmias. Journal of the<br />
American College of Cardiology 1998; 31 (2A): 38A<br />
M. M. Gallagher, B.J. Hennessy, C.M. Hart, M.S. Shannon, A.M. Murtagh, <strong>Obel</strong><br />
OA, A.J. Camm. Embolic Complications of Direct Current Cardioversion Reflect<br />
Inadequate Intensity of Anticoagulation Circulation; 1998, 17 (Suppl): 767<br />
<strong>Obel</strong> OA, Mansour M, Picard M, Ruskin JR, Keane D Persistence of Septal<br />
Defects After Transeptal Puncture for Pulmonary Vein Isolation Procedures<br />
NASPE 2004<br />
Abrol R, Nguyen C, Le B, Cogan J, Nesbitt W, Naseem R, Hamden M, Kowal R,<br />
<strong>Obel</strong> OA, Anderson JA, Joglar J. Radiation exposure to physician operators<br />
during biventricular device implants. 2005 Heart Rhythm Society Scientific<br />
Sessions; May 4-7,2005; New Orleans, LA. Abstract P2-114<br />
Nesbitt W, Lampe C, <strong>Obel</strong> OA. Impantation of Left ventricular Pacing Leads<br />
Without the Use of a Sheath Heart Rhythm Journal 2006; 3 (1S) S143<br />
<strong>Obel</strong> IWP, Daniels J, Lokhoff N, Van Wijk F, <strong>Obel</strong> OA. Initial Experience With a<br />
Single Coronary Sinus Lead for Left-Sided Atrioventricular Pacing. Heart Rhythm<br />
Journal 2007 (5S) S25<br />
8
Srinivasan N, Ho J, Naseem R, Joglar J, Collins L, <strong>Obel</strong> OA. AV Node Ablation<br />
and Biventricular Pacing − A Comparison between Ischemic and Non-Ischemic<br />
Cardiomyopathy - Heart Rhythm Journal 2009 5S S463<br />
Ahmed SH, Amin A, Joglar J, <strong>Obel</strong> OA. Does Interatrial Conduction Delay<br />
Preclude Atrioventricular Optimization in Cardiac Resynchronization Therapy,<br />
and Would a Left Atrial Bipole Help? - Heart Rhythm Journal 2009 5S S188<br />
Torres-Heisecke R, Dimas,V MD; <strong>Owen</strong>s A, Joglar,J; <strong>Obel</strong> OA. Unexpected<br />
Restoration of Sinus Rhythm After Atrioventricular Node Ablation and<br />
Biventricular Pacing in Heart Failure Patients With Atrial Fibrillation. (ACC March<br />
2010)<br />
Presentations, Lectureship<br />
September 1999 – ‘Fighting Sudden Cardiac Death – a Worldwide Challenge’,<br />
Palais de Congress, Paris – 3 lectures on behalf of Prof AJ Camm<br />
Numerous presentations at international meetings including AHA, ACC,<br />
NASPE/HRS, The British Cardiac Society, and the European Society of<br />
Cardiology (see ‘Abstracts’)<br />
Internal Medicine Grand Rounds, <strong>UT</strong> <strong>Southwestern</strong>, Dallas, Texas, March 2006,<br />
January 2011<br />
Internal Medicine Grand Rounds, Presbyterian Hospital, Dallas, Texas, March<br />
2006<br />
Regular presenter at IBHRE Exam Review Courses<br />
Numerous lectures delivered for Pacing/ICD/ablation catheter corporations at<br />
sponsored symposia<br />
Presenter at core curricula sessions at HRS scientific sessions in 2007 and 2008;<br />
session chairman in 2009, 2010<br />
Other Previous Training<br />
General Medicine<br />
Feb’94 – Jan’96 Registrar in General Medicine<br />
Trent Regional Health Authority, UK<br />
Feb ’93 – Jan ’94 Senior House <strong>Of</strong>ficer, Medicine<br />
Kent & Canterbury Hospital, UK<br />
Aug ’92 – Jan ’93 Senior House <strong>Of</strong>ficer in Medicine<br />
9
Bradford Royal Infirmary, UK<br />
Aug ’91 – Mar ’92 Senior House <strong>Of</strong>ficer in Medicine<br />
William Harvey Hospital, Ashford, UK<br />
Feb ’91 – July ’91 Senior House <strong>Of</strong>ficer, Orthopedics<br />
William Harvey Hospital, Ashford, UK<br />
Feb ’89 – Jan ‘91 Compulsory Military Service (MD in a Mission Hospital<br />
in Zululand, South Africa)<br />
1 Jan ‘88 – 30 June ‘88 Senior House <strong>Of</strong>ficer, Medicine<br />
Hillbrow Hospital, Johannesburg, South Africa<br />
1 Jan ‘87 – 31 Dec ‘87 Internship (Medicine and Surgery)<br />
Hillbrow Hospital, Johannesburg, South Africa<br />
Other interests<br />
Family, music, travel, photography<br />
Referees<br />
Dr Vivek Reddy<br />
Mount Sinai Medical Center<br />
1190 5 th Avenue<br />
1 st Floor, New York, NY 10029<br />
Tel: 212 241 7114<br />
Professor A John Camm<br />
Department of Cardiological Sciences<br />
St George’s Hospital Medical School<br />
LONDON<br />
SW17 0RE<br />
UK<br />
Tel: (+44) 208 725 3554<br />
Dr Jeremy Ruskin<br />
Cardiac Arrhythmia Service<br />
Massachusetts General Hospital<br />
55 Fruit Street<br />
Boston<br />
02130<br />
Massachusetts<br />
USA<br />
Tel: 617 726 2000<br />
10