SIEVE User Guide
SIEVE User Guide
SIEVE User Guide
Create successful ePaper yourself
Turn your PDF publications into a flip-book with our unique Google optimized e-Paper software.
Overview to <strong>SIEVE</strong><br />
<strong>SIEVE</strong> software performs semi-quantitative differential analyses of sample populations by<br />
comparing spectral information from LC/MS analyses of control (healthy) and disease<br />
(treatment) samples. Any changes between the two sample sets indicate a differential protein<br />
expression. Elements from raw files that show significant statistical differences are sent for a<br />
SEQUEST ® database search to determine peptide and protein identification.<br />
The following sections provide a high-level overview of <strong>SIEVE</strong>:<br />
• Understanding <strong>SIEVE</strong><br />
• About the <strong>SIEVE</strong> Procedure<br />
Thermo Scientific <strong>SIEVE</strong> <strong>User</strong> <strong>Guide</strong> 1<br />
1
Change language