A5V4d

Feverish illness in children
Table 5.37 GRADE profile for evaluation of poor peripheral circulation
Number
of
studies
86
Number
of
children
Sensitivity
(95%
confidence
interval)
Poor peripheral circulation
For detecting serious bacterial infection
1
(Bleeker,
2001)
231 11 (6 to 16)
a
Specificity
(95%
confidence
interval)
78 (69 to
88) a
Positive
predictive
value
(95%
confidence
interval)
59 (42 to
76) a
Negative
predictive
value
(95%
confidence
interval)
23 (17 to
28) a
Positive
likelihood
ratio
(95%
confidence
interval)
0.5 (0.3 to
0.9) a
a Calculated by a member of the technical team at the NCC-WCH based on results reported in the study
Table 3.38 GRADE profile for evaluation of bulging abdomen
Number
of
studies
Number
of
children
Bulging abdomen
Sensitivity
(95%
confidence
interval)
For detecting serious bacterial infection
1
(Bleeker,
2001)
Specificity
(95%
confidence
interval)
231 6 (2 to 9) a 88 (80 to 96)
a
Positive
predictive
value
(95%
confidence
interval)
59 (35 to
82) a
Negative
predictive
value
(95%
confidence
interval)
24 (18 to
30) a
Positive
likelihood
ratio
(95%
confidence
interval)
0.5 (0.2 to
1.2) a
a Calculated by a member of the technical team at the NCC-WCH based on results reported in the study
Table 5.39 GRADE profile for evaluation of paresis or paralysis
Number
of
studies
Number
of
children
Paresis or paralysis
Sensitivity
(95%
confidence
interval)
For detecting bacterial meningitis
1
(Offringa
, 1992)
92 30 (12 to 49)
a
Specificity
(95%
confidence
interval)
91 (85 to
98) a
Positive
predictive
value
(95%
confidence
interval)
54 (27 to
81) a
Negative
predictive
value
(95%
confidence
interval)
80 (71 to
89) a
Positive
likelihood
ratio
(95%
confidence
interval)
3.5 (1.3 to
9.4) a
a Calculated by a member of the technical team at the NCC-WCH based on results reported in the study
Negative
likelihood
ratio
(95%
confidence
interval)
1.1 (1.0 to
1.3) a
Negative
likelihood
ratio
(95%
confidence
interval)
1.1 (1.0 to
1.2) a
Negative
likelihood
ratio
(95%
confidence
interval)
0.8 (0.6 to
1.0) a
Quality
Very
low
Quality
Very
low
Quality
Very
low