A5V4d

Number
of
studies
Number
of
children
Sensitivity
(95%
confidence
interval)
Specificity
(95%
confidence
interval)
For detecting bacteraemia or bacterial meningitis
1
(Pantell,
2004)
3066 61 (48 to
73) a
Temperature > 38.5°C
For detecting bacterial meningitis
1 (Wells,
2001)
218 58 (39 to
78)
Temperature ≥ 39.0°C
For detecting urinary tract infection
1 (Shaw,
1998)
1
(Newma
n, 2002)
2411 79 (70 to
88) a
1666 40 (32 to
47) a
For detecting serious infection
1
(Thomps
on,
2009)
700 27 (22 to
32)
69 (67 to
71) a
81 (75 to
86)
33 (31 to
35) a
74 (72 to
76) a
87 (84 to
91)
Positive
predictive
value
(95%
confidence
interval)
Clinical assessment of the child with fever
Negative
predictive
value
(95%
confidence
interval)
4 (3 to 5) a 99 (98 to
99) a
27 (15 to
40)
94 (88 to
100)
9 (3 to 5) a 98 (97 to
99) a
14 (11 to
17) a
41 (30 to
51) a
For detecting pneumonia, urinary tract infection or bacteraemia
1 (Craig,
2010)
12807 54 (51 to
57) a
58 (58 to
59) a
For detecting bacteraemia or bacterial meningitis
1
(Pantell,
2004)
3066 16 (7 to 26)
a
Temperature > 39.0°C
For detecting serious disease
1
(Nademi,
2001)
90 (88 to
91) a
141 14 (3 to 25) 82 (74 to
89)
For detecting bacteraemia or bacterial meningitis
1
(Pantell,
2004)
3066 43 (31 to
55) a
For detecting urinary tract infection
1 (Zorc,
2005)
1025 37 (27 to
47) a
81 (79 to
82) a
81 (78 to
83) a
92 (90 to
94) a
82 (78 to
85) a
9 (9 to 10) a 94 (94 to
95) a
3 (1 to 5) a 98 (97 to
99) a
25 (7 to 42) 70 (61 to
78)
4 (3 to 6) a 99 (98 to
99) a
16 (11 to
21) a
93 (91 to
95) a
Positive
likelihood
ratio
(95%
confidence
interval)
2.0 (1.6 to
2.4) a
3.1 (2.0 to
4.8) a
1.2 (1.0 to
1.3) a
1.5 (1.2 to
1.9) a
2.1 (1.5 to
2.9)
1.3 (1.2 to
1.4) a
1.6 (0.9 to
2.8) a
0.8 (0.3 to
1.9) a
2.2 (1.7 to
3.0) a
2.0 (1.4 to
2.6) a
Negative
likelihood
ratio
(95%
confidence
interval)
0.6 (0.4 to
0.8) a
0.5 (0.3 to
0.8) a
0.6 (0.4 to
1.0) a
0.8 (0.7 to
0.9)
0.8 (0.8 to
0.9)
0.8 (0.7 to
0.8) a
0.9 (0.8 to
1.0) a
1.0 (0.9 to
1.2) a
0.7 (0.6 to
0.9) a
0.8 (0.7 to
0.9) a
Quality
Low
Low
Modera
te
Modera
te
Low
Low
Low
Very
low
Low
Modera
te
75