A5V4d

Feverish illness in children
Number
of
studies
74
Number
of
children
Temperature > 37.5°C
Sensitivity
(95%
confidence
interval)
For detecting bacterial meningitis
1 (Wells,
2001)
218 79 (63 to
95)
Temperature ≥ 38.0°C
Specificity
(95%
confidence
interval)
55 (48 to
62)
Positive
predictive
value
(95%
confidence
interval)
18 (11 to
25)
For detecting pneumonia, urinary tract infection or bacteraemia
1 (Craig,
2010)
12807 85 (83 to
87) a
For detecting urinary tract infection
1
(Newma
n, 2002)
1666 100 (100 to
100) a
22 (22 to
23) a
0 (0 to 0) a 10 (8 to 11)
a
For detecting bacteraemia or bacterial meningitis
1
(Pantell,
2004)
3066 90 (83 to
98) a
For detecting serious bacterial infection
1
(Stanley,
2005)
For detecting sepsis
1
(Weber,
2003)
5279 100 (100 to
100) a
29 (28 to
31) a
Negative
predictive
value
(95%
confidence
interval)
95 (88 to
100)
8 (7 to 8) a 95 (94 to
96) a
3 (2 to 3) a 99 (99 to
100) a
Positive
likelihood
ratio
(95%
confidence
interval)
1.7 (1.3 to
2.3) a
1.1 (1.1 to
1.1) a
NC 1.0 (1.0 to
1.0) a
1.3 (1.2 to
1.4) a
0 (0 to 0) a 9 (8 to 10) a NC 1.0 (1.0 to
1.0) a
Negative
likelihood
ratio
(95%
confidence
interval)
0.4 (0.2 to
0.8) a
0.7 (0.6 to
0.8) a
Quality
Low
Low
NC Modera
te
0.3 (0.2 to
0.7) a
Low
NC Very
low
3303 NR/NC h NR/NC h NR/NC h NR/NC h NR/NC h NR/NC h Low
For detecting bacterial meningitis
1
(Weber,
2003)
3303 NR/NC i NR/NC i NR/NC i NR/NC i NR/NC i NR/NC i Low
Temperature ≥ 38.4°C
For detecting urinary tract infection
1
(Shettiga
r, 2011)
334 78 (62 to
93)
Temperature ≥ 38.5°C
For detecting serious bacterial infection
1 (Brent,
2011)
1716 38 (27 to
50)
For detecting urinary tract infection
1
(Newma
n, 2002)
1666 77 (71 to
84) a
41 (36 to
47)
85 (83 to
86)
38 (35 to
40) a
10 (6 to 15) 95 (92 to
99)
9 (6 to 13) 97 (96 to
98)
12 (10 to
14) a
94 (92 to
96) a
1.3 (1.1 to
1.6)
2.5 (1.1 to
5.7)
1.2 (1.1 to
1.4) a
0.5 (0.3 to
1.1)
0.7 (0.3 to
1.7)
0.6 (0.5 to
0.8) a
Modera
te
Very
low
Modera
te