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Abbreviations and glossary<br />

Standard deviation A measure of the spread, scatter or variability of a set of measurements.<br />

Usually used with the mean (average) to describe numerical data.<br />

Statistical power The ability of a study to demonstrate an association or causal relationship<br />

between two variables, given that an association exists. For example, 80%<br />

power in a clinical trial means that the study has a 80% chance of ending up<br />

with a P value of less than 5% in a statistical test (i.e. a statistically significant<br />

treatment effect) if there really was an important difference (e.g. 10% versus<br />

5% mortality) between treatments. If the statistical power of a study is low, the<br />

study results will be questionable (the study might have been too small to<br />

detect any differences). By convention, 80% is an acceptable level of power.<br />

Structured interview A research technique where the interviewer controls the interview by adhering<br />

strictly to a questionnaire or interview schedule with pre-set questions.<br />

Study checklist A list of questions addressing the key aspects of the research methodology that<br />

must be in place if a study is to be accepted as valid. A different checklist is<br />

required for each study type. These checklists are used to ensure a degree of<br />

consistency in the way that studies are evaluated.<br />

Study population People who have been identified as the subjects of a study.<br />

Study quality See methodological quality.<br />

Study type The kind of design used for a study. Randomised controlled trials, case–control<br />

studies and cohort studies are all examples of study types.<br />

Subject A person who takes part in an experiment or research study.<br />

Survey A study in which information is systematically collected from people (usually<br />

from a sample within a defined population).<br />

Symptom A patient’s report of an abnormal feeling or sensation that provides the clinician<br />

with a subjective indication of a particular diagnosis or disorder (cf. sign).<br />

Systematic Methodical, according to plan; not random.<br />

Systematic error Refers to the various errors or biases inherent in a study. See also bias.<br />

Systematic review A review in which evidence from scientific studies has been identified,<br />

appraised and synthesised in a methodical way according to predetermined<br />

criteria. May or may not include a meta-analysis.<br />

Systemic Involving the whole body.<br />

Tachypnoea Abnormally rapid respiratory rate.<br />

Target population The people to whom guideline recommendations are intended to apply.<br />

Recommendations may be less valid if applied to a population with different<br />

characteristics from the participants in the research study, for example in terms<br />

of age, disease state or social background.<br />

Tepid sponging A traditional treatment for fever in which the patient is undressed and sponged<br />

with lukewarm water that is then allowed to evaporate.<br />

Tertiary centre A major medical centre providing complex treatments that receives referrals<br />

from both primary and secondary care. Sometimes called a tertiary referral<br />

centre. See also primary care and secondary care.<br />

Triangulation Use of three or more different research methods in combination; principally<br />

used as a check of validity. The more the different methods produce similar<br />

results, the more valid the findings.<br />

Triple-blind study A study in which the statistical analysis is carried out without knowing which<br />

treatment patients received, in addition to the patients and<br />

investigators/clinicians being unaware which treatment patients were getting.<br />

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