A5V4d

Feverish illness in children
Number of studies Number of children Effect *
Temperature AUC
0 to 8 hours
1 (Kauffman et al.,
1992)
1 (Kauffman et al.,
1992)
0 to 6 hours
1 (Wilson et al.,
1991)
1 (Wilson et al.,
1991)
0 to 8 hours
1 (Walson et al.,
1989)
1 (Walson et al.,
1989)
214
Ibuprofen Paracetamol Relative
(95% confidence
interval)
730 (576 to
839) a
590 (160 to
875) l
7.09 (SEM
0.58), n = 43 g
4.91 (SEM
0.47), n = 47 l
460.9 g
510.9 l
328 (-356 to
686) b
328 (-356 to
686) b
6.72 (SEM
0.58), n = 51 h
6.72 (SEM
0.58), n = 51 h
365.0 b
365.0 b
0 to 6 hours – total temperature change per hour
1 (Walson et al.,
1992)
1 (Walson et al.,
1992)
297 g
Absolute
(95%
confidence
interval)
Quality
p = 0.05 - Very low
p = 0.05 - Very low
NS - Very Low
NS - Very low
NS - Low
p < 0.05 - Low
377 b NS - Moderate
385 l 377 b NS - Moderate
0 to 12 hours – total temperature change per hour
1 (Walson et al.,
1992)
1 (Walson et al.,
1992)
689 g 938 n p