A5V4d

Number of studies Number of children Effect *
Mean temperature at > 24 hours
Day 2
1 (Sarrell et al.,
2006)
Day 3
1 (Sarrell et al.,
2006)
Afebrile at 1 to 2 hours
1 hour
1 (Autret et al.,
1997)
2 hours
1 (Wong et al.,
2001)
1 (Van Esch et al.,
1995)
Afebrile at > 2 to 5 hours
4 hours
1 (Autret et al.,
1997)
1 (Van Esch et al.,
1995)
1 (Vauzelle-
Kervroedan et al.,
1997)
Afebrile at > 5 to 24 hours
6 hours
1 (Autret et al.,
1997)
1 (Van Esch et al.,
1995)
12 hours
1 (Van Esch et al.,
1995)
24 hours
1 (Van Esch et al.,
1995)
Afebrile at > 24 hours
No data
Ibuprofen Paracetamol Relative
(95% confidence
interval)
39.66°C (SD
1.48), n = 155 g
39.64°C (SD
1.46), n = 155 g
33 of 116 a
145 of 185 i
27 of 30 g
39.74°C (SD
1.37), n = 154 h
39.34°C (SD
1.19) n = 154 h
25 of 113 b
130 of 191 j
22 of 29 b
SMD -0.06 (-0.28 to
+0.17)
SMD 0.22 (0.00 to
+0.45)
Antipyretic interventions
Absolute
(95%
confidence
interval)
Quality
- High
- High
RR 1.29 (0.82, 2.02) - Low
RR 1.15 (1.02, 1.30) - Moderate
RR 1.19 (0.94, 1.50) b - Very low
69 of 116 a 45 of 113 b RR 1.49 (1.14, 1.96) - Low
26 of 30 g 22 of 29 b
56 of 58 l
43 of 116 a
20 of 34 g
21 of 34 g
20 of 34 g
53 of 55 b
40 of 113 b
18 of 35 b
24 of 35 b
20 of 35 b
RR 1.18 (0.90, 1.55) - Very low
RR 1.00 (0.93, 1.08) - Moderate
RR 1.05 (0.74, 1.48) - Low
RR 1.14 (0.75, 1.75) - Very low
RR 0.96 (0.68, 1.34) - Very low
RR 1.22 (0.86, 1.74) - Very low
213