A5V4d

Number of studies Number of children Effect *
1 (Autret et al.,
1994)
1 (McIntyre et al.,
1996)
1 (Nadal et al.,
2002)
1 (Wong et al.,
2001)
5 hours
1 (Wong et al.,
2001)
1 (Wilson et al.,
1991)
1 (Wilson et al.,
1991)
Ibuprofen Paracetamol Relative
(95% confidence
interval)
-1.32°C (SD
1.00), n = 77 a
-1.80°C (SD -),
n = 76 m
-1.30°C (SD
1.1), n = 94 o
-1.44°C (SD
0.98), n = 185 i
-1.35°C (SD
1.06), n = 185 i
-1.4 (SD
0.6856), n = 47
g
-1.1
(SD0.6557),
n = 43 l
Mean change in temperature at > 5 to 24 hours
6 hours
1 (Autret et al.,
1997)
-1.19°C (SD
0.94), n = 108 a
1 (Wong et al., 2001 -1.24°C (SD
1.08), n=185 i
1 (Wilson et al.,
1991)
1 (Wilson et al.,
1991)
-1.1 (SD
0.6557), n = 43 g
-1.2 (SD
0.6856), n = 47 l
Mean change in temperature at > 24 hours
No studies found
Mean temperature at 1 to 2 hours
1 hour
1 (Kauffman et al.,
1992)
1 (Kauffman et al.,
1992)
1 (Vauzelle-
Kervrodan et al.,
1997)
38.0ºC (SD
0.6928), n = 12 a
37.9 (SD
0.4243), n = 8 l
38.4°C (SD
0.6) n = 60 a
-1.02°C (SD
1.05), n = 74 b
-1.6°C (SD -),
n = 74 n
-1.20°C (SD
0.96), n = 93 p
-1.47°C (SD
0.91), n = 191 j
-1.34°C (SD
1.05) j n = 191 j
-1.0 (SD
1.4422), n = 52 h
-1.0 (SD
1.4422), n = 52 h
-0.88°C (SD
0.85), n=108 b
-1.20°C (SD
1.09) n=191 j
-0.9 (SD
1.4422), n = 52 h
-0.9 (SD
1.4422), n = 52 h
38.2°C (SD
0.5657), n = 8 b
38.2 (SD
0.5657), n = 8 b
38.3°C (SD
0.6), n = 56 b
SMD -0.29 (-0.61 to
+0.03)
Antipyretic interventions
Absolute
(95%
confidence
interval)
Quality
- Low
P = 0.39 - Moderate
SMD -0.10 (-0.38 to
+0.19)
SMD 0.03 (-0.17 to
+0.23)
SMD -0.01 (-0.21 to
+0.19)
SMD -0.35 (-0.74 to
+0.05)
SMD -0.09 (-0.49 to
+0.32)
SMD -0.34 (-0.61 to -
0.08)
SMD -0.04 (-0.24 to
+0.17)
SMD -0.17 (-0.58 to
+0.23)
SMD -0.26 (-0.66 to
+0.14)
SMD -0.30 (-1.20 to
+0.60)
SMD -0.57 (-1.57 to
+0.44)
SMD: 0.17 (-0.20 to
+0.53)
- Very low
- Moderate
- Moderate
- Very low
- Very low
- Low
- Moderate
- Very low
- Very low
- Very low
- Very low
- Low
209