A5V4d

Feverish illness in children
Number of studies Number of children Effect *
1 (Wong et al.,
2001)
1 (Erlewyn-
Lajeunesse et al.,
2006)
1 (Wilson et al.,
1991)
1 (Wilson et al.,
1991)
1.5 hours
1 (Wong et al.,
2001)
2 hours
1 (Wong et al.,
2001)
1 (Wilson et al.,
1991)
1 (Wilson et al.,
1991)
208
Ibuprofen Paracetamol Relative
(95% confidence
interval)
-1.00°C (SD
0.65), n=185 i
-0.92°C
(95% CI 0.70 to
1.14), n=35 g
-0.8 (SD
0.3279), n = 43 g
-0.8 (SD
0.3428), n = 47
l
-1.33°C
(SD 0.66),
n=185 i
-1.56°C (SD
0.72), n = 185 i
-1.2 (SD
0.6557), n = 43 g
-1.2 (SD
0.6856), n = 47 l
-1.05°C (SD
0.70), n=191 j
-0.95°C
(95% CI 0.72 to
1.17), n=37 k
-0.8 (SD
0.3606), n = 52 h
-0.8 (SD
0.3606), n = 52 h
-1.33°C
Mean change in temperature at > 2 to 5 hours
3 hours
1 (Wong et al.,
2001)
1 (Wilson et al.,
1991)
1 (Wilson et al.,
1991)
4 hours
1 (Autret et al.,
1997)
1 (Wilson et al.,
1991)
1 (Wilson et al.,
1991)
1 (Ulukol et al.,
1999)
-1.58°C (SD
0.81), n=185 i
-1.5 (SD
0.6856), n = 47 g
-1.4 (SD
0.6557), n = 43 l
-1.42°C (SD
0.85)
n=112 a
-1.6 (SD
0.6856), n = 47 g
-1.2 (SD
0.6557), n = 43 l
-1.86°C (SD
0.74) n = 30 l
(SD 0.68)
n=191 j
-1.55°C (SD
0.68) n = 191 j
-1.2 (SD
0.7211), n = 52 h
-1.2 (SD
0.7211), n = 52 h
-1.52°C (SD
0.79) n=191 j
-1.4 (SD
0.7211), n = 52 h
-1.4 (SD
0.7211), n = 52 h
-1.04°C (SD
0.85)
n= 110 b
-1.3 (SD
1.4422), n = 52 h
-1.3 (SD
1.4422), n = 52 h
-1.29°C (SD
0.71)
n= 30 b
SMD 0.07 (-0.13 to
+0.28)
SMD 0.04 (-0.42 to
+0.51)
SMD 0.04 (-0.42 to
+0.51)
SMD 0.00 (-0.40 to
+0.40)
SMD 0.00 (-0.20 to
+0.20)
SMD: -0.01 (-0.22 to
+0.19)
SMD 0.00 (-0.40 to
+0.40)
SMD 0.00 (-0.39 to
+0.39)
SMD -0.07 (-0.28 to
+0.13)
Absolute
(95%
confidence
interval)
Quality
- Moderate
- Low
- Very low
- Very low
-
Moderate
- Moderate
- Very low
- Very low
- Moderate
-0.14 (-0.54 to +0.25) - Very low
0.00 (-0.40 to +0.40) - Very low
SMD -0.45 (-0.71 to
-0.18)
SMD -0.26 (-0.66 to
+0.14)
SMD 0.09 (-0.32 to
+0.49)
SMD 0.78 (+0.25 to
+1.30)
- Very low
Very low
- Very low
- Low