A5V4d

Number of studies Number of children Effect a
4 hours
1 (Walson et al.,
1989)
1 (Walson et al.,
1989)
5 hours
1 (Walson et al.,
1989)
1 (Walson et al.,
1989)
Intervention Control Relative
(95% confidence
interval)
99.5ºF (SD 1.6)
n = 29 b
99.2ºF (SD 1.2)
n = 25 e
99.8ºF (SD 1.9)
n = 29 b
99.3ºF (SD 1.7
n = 25 e
Mean temperature at > 5 to 24 hours
6 hours
1 (Walson et al.,
1989)
1 (Walson et al.,
1989)
7 hours
1 (Walson et al.,
1989)
1 (Walson et al.,
1989)
100.2ºF (SD
2.2) n = 29 b
99.7ºF (SD 1.9)
n = 25 d
101.2ºF (SD
2.0) n = 29 b
100.6ºF (SD
2.2) n = 25 d
Mean temperature at > 24 hours
No data
Afebrile at 1 to 2 hours
No data
Afebrile at > 2 to 5 hours
No data
Afebrile at > 5 to 24 hours
No data
Afebrile at > 24 hours
No data
Temperature area under the curve
0 to 8 hours
1 (Kauffman et al.,
1992)
1 (Kauffman et al.,
1992)
730 (576 to
839) f
590 (160 to
875) d
101.6ºF (SD
1.5) n = 33 c
101.6ºF (SD
1.5) n = 33 c
101.3ºF (SD
1.6) n = 33 c
101.3ºF (SD 1.6
n = 33 c
101.2ºF (SD
1.5) n = 33 c
101.2ºF (SD
1.5) n = 33 c
101.2ºF (SD
1.7) n = 33 c
101.2ºF (SD
1.7) n = 33 c
-67 (-629 to
120) c
-67 (-629 to 120
c
SMD -1.34 (-1.90
to -0.78)
SMD -1.72 (-2.33
to -1.10)
SMD -0.85 (-1.37
to -0.33)
SMD -1.20 (-1.77
to -0.63)
SMD -0.53 (-1.04
to -0.02)
SMD -0.88 (-1.42
to -0.33)
SMD 0.00 (-0.50 to
+0.50)
SMD -0.31 (-0.83
to +0.22)
Antipyretic interventions
Absolute
(95%
confidence
interval)
Quality
- Moderate
- Moderate
- Moderate
- Moderate
- Moderate
- Moderate
- Low
- Low
P < 0.01 - Low
P < 0.01 - Low
205