A5V4d

Feverish illness in children
Number of studies Number of children Effect *
1 (Kauffman et al.,
1992)
202
Paracetamol Placebo Relative risk
(95% confidence
interval)
38.1ºC (SD
0.5657),
n = 8 c
Mean in temperature at > 5 to 24 hours
6 hours
1 (Walson et al.,
1989a)
1 (Gupta et al.,
2007)
1 (Kauffman., et al.,
1992)
8 hours
1 (Walson et al.,
1989a)
1 (Kauffman et al.,
1992)
100.8ºF (SD
1.9), n = 31 c
37.7ºC (SD
0.7), n = 101 a
38.5ºC (SD
1.1314),
n = 8 c
101.6ºF (SD
1.8), n =31 c
38.8ºC (SD
0.8485),
n = 8 c
Mean in temperature at > 24 hours
No data
Mean change temperature at 1 to 2 hours
2 hours
1 (Gupta et al.,
2007)
70.3% (SD
24.8), n = 101
a
Mean change temperature at > 2 to 5 hours
4 hours
1 (Gupta et al.,
2007)
85.4% (SD
22.4), n = 101
a
Mean change temperature at > 5 to 24 hours
6 hours
1 (Gupta et al.,
2007)
87.6%
(SD18.6),
n = 101 a
Mean change temperature at > 24 hours
No data
Afebrile at 1 to 2 hours
No data
39.4ºC (SD
0.9), n = 9 b
101.2ºF (SD
1.5), n = 33 b
38.3ºC (SD
1.0), n = 102 b
39.3ºC (SD
0.6),
n = 9 b
101.2ºF (SD
1.7), n = 33 b
39.2ºC (SD
0.6),
n = 9 b
30.7% (SD
26.1), n = 102 b
45.5% (SD
34.1), n = 102 b
51.0% (SD
33.3), n = 102 b
SMD -1.62 (-2.76 to
-0.48)
SMD -0.23 (-0.72 to
0.26)
SMD -0.69 (-0.98 to
-0.41)
SMD -0.85 (-1.86 to
+0.15)
SMD 0.23 (-0.27 to
+0.72)
SMD -0.52 (-1.50 to
+0.45)
SMD 1.55 (+1.24 to
+1.86)
SMD 1.38 (+1.68 to
+1.07)
SMD 1.35 (+1.66 to
+1.04)
Absolute
(95%
confidence
interval)
Quality
- Very
Low
- Low
- Low
- Very
Low
- Very
Low
- Very
Low
- High
- High
- High