A5V4d

Number
of
studies
Number
of
children
Sensitivity
(95%
confidence
interval)
Specificity
(95%
confidence
interval)
Positive
predictive
value
(95%
confidence
interval)
Management by the paediatric specialist
Negative
predictive
value (95%
confidence
interval)
Positive
likelihood
ratio
(95%
confidence
interval)
Negative
likelihood
ratio
(95%
confidence
interval)
Invasive bacterial infections: Bacterial meningitis, occult bacteremia & sepis. Prevalence = 1.7%
≥ 20 mg/L
1
(Luaces-
Cubells
et al,
2012)
≥ 40 mg/L
1
(Luaces-
Cubells
et al,
2012)
≥ 80 mg/L
1
(Luaces-
Cubells
et al,
2012)
≥ 91 mg/L
1
(Luaces-
Cubells
et al,
2012)
N = 868 0.80 (0.52
to 0.96)
N = 868 0.47 (0.21
to 0.73)
N = 868 0.33 (0.12
to 0.62)
N = 868 0.33 (0.12
to 0.62)
0.66 (0.63
to 0.69)
0.83 (0.80
to 0.85)
0.95 (0.93
to 0.96)
0.96 (0.94
to 0.97)
0.04 (0.02
to 0.07) a
0.05 (0.02
to 0.10) a
0.10 (0.04
to 0.23) a
0.13 (0.05
to 0.28) a
0.99 (0.98
to 1.00) a
0.99 (0.98
to 0.99) a
0.99 (0.98
to 0.99) a
0.99 (0.98
to 0.99) a
CI confidence interval, UTI urinary tract infection
a Estimates and confidence intervals were calculated by the NCC-WCH technical team.
b Confidence intervals were calculated by the NCC-WCH technical team.
2.36 (1.80
to 3.09) a
2.72 (1.55
to 4.76) a
6.45 (2.98
to 13.97) a
8.16 (3.71
to 17.93) a
0.30 (0.11 to
0.83) a
0.64 (0.40 to
1.03) a
0.70 (0.49 to
1.01) a
0.70 (0.49 to
0.99) a
Quality
Low
Low
Low
Low
167