A5V4d

Feverish illness in children
Number
of
studies
7 mg/dl
1 (Pratt
et al,
2007)
166
Number
of
children
3 mg/dl < 12 hours
1 (Pratt
et al,
2007)
5 mg/dl
1 (Pratt
et al,
2007)
7 mg/dl
1 (Pratt
et al,
2007)
3 mg/dl > 12 hours
1 (Pratt
et al,
2007)
5mg/dl
1 (Pratt
et al,
2007)
7 mg/dl
1 (Pratt
et al,
2007)
Sensitivity
(95%
confidence
interval)
N = 119 59 (33 to
81)
N = 45 67 (24 to
94)
N = 45 50 (14 to
86)
Specificity
(95%
confidence
interval)
87 (79 to
93)
74 (58 to
86)
92 (78 to
98)
N = 45 33 (6 to 76) 97 (85 to
100)
N = 74 100 (72 to
100)
N = 74 82 (48 to
97)
N = 74 73 (40 to
93)
63 (50 to
75)
79 (67 to
88)
81 (69 to
89)
Positive
predictive
value
(95%
confidence
interval)
43 (24 to
65)
Negative
predictive
value (95%
confidence
interval)
93 (85 to
97)
28 (5 to 52) 94 (85 to
102)
50 (10 to
90)
67 (13 to
120)
32 (17 to
48)
41 (20 to
61)
40 (19 to
61)
Occult bacteremia, UTI, Pneumonia. Prevalence = 11.3%
4.4 mg/dl
1
(Isaacma
n et al,
2002)
N = 256 63 (43 to
82)
81 (76 to
87)
30 (18 to
43)
Occult bacteremia, UTI, Pneumonia. Prevalence = 18%
7 mg/dl
1
(Pulliam
et al,
2001)
N = 77 79 (49 to
94.2)
91 (79.8 to
96)
65 (38.3 to
85.8)
92 (84 to
101)
90 (82 to
99)
100 (98 to
101)
96 (91 to
101)
94 (88 to
101)
94 (91 to
98)
95 (86.1 to
99)
Positive
likelihood
ratio
(95%
confidence
interval)
4.6 (2.4 to
8.8)
2.6 (1 to
5.2)
6.5 (1.7 to
22.3)
13 (1.8 to
88.4)
2.7 (1.7 to
3.8)
4 (2.1 to
6.9)
3.8 (1.9 to
7)
3.3 (2.2 to
4.8)
8.3 (3.8 to
27.3)
Negative
likelihood
ratio
(95%
confidence
interval)
0.47 (0.27 to
0.83)
0.4 (0.1 to
1.4)
0.5 (0.2 to
1.2)
0.7 (0.4 to
1.2)
0.0 (0.0 to
6.8)
0.2 (0.1 to
0.8)
0.3 (0.1 to
0.9)
0.5 (0.3 to
0.7)
0.2 (0.1 to
0.6)
Quality
Very
Low
Very
Low
Very
Low
Very
Low
Very
Low
Very
Low
Very
Low
Low
Low