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Clinical assessment of the child with fever<br />

Figure 5.2 Admission temperature and pulse of children with meningococcal septicaemia, superimposed on<br />

proposed age-specific temperature–pulse centile charts. GMSP, Glasgow Meningococcal Septicaemia<br />

Prognostic score. (Brent et al., 2011) (Reproduced under open access publishing agreements)<br />

(Brent et al., 2011) (Reproduced under open access publishing agreements)<br />

(Brent et al., 2011, Evaluation of temperature–pulse centile charts in identifying serious bacterial illness: observational cohort<br />

study Arch Dis Child 2011;96:368-373) (Reproduced under the open access publishing agreements)<br />

Evidence profile<br />

The GRADE profiles presented show results of included studies for the review question.<br />

Table 5.59 − GRADE profile for the distribution of age-specific heart rate temperature<br />

data by centile group for 1360 children presenting at a paediatric emergency department<br />

with suspected serious bacterial infection for the detection of serious illness.<br />

Table 5.60 − GRADE profile reporting the sensitivity, specificity, positive and negative<br />

likelihood ratio for significant bacterial infection of cut-offs defined by heart rate and<br />

body temperature for 1360 children presenting at a paediatric emergency department<br />

with suspected serious bacterial infection.<br />

Table 5.61 − GRADE profile for the sensitivity of cut-offs defined by heart rate and body<br />

temperature centiles and tachycardia for detecting children with meningococcal<br />

septicaemia of various degrees of severity in 325 children presenting to hospital with<br />

meningitis.<br />

121<br />

2013 Update

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