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Book of Medical Disorders in Pregnancy - Tintash

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pregnancy. The <strong>in</strong>crease <strong>in</strong> volume is<br />

probably due to <strong>in</strong>creased production <strong>of</strong><br />

aldosterone which occurs <strong>in</strong> normal<br />

pregnancy. Estrogens also play some<br />

part <strong>in</strong> <strong>in</strong>creas<strong>in</strong>g this volume.<br />

Blood corpuscles - The white cells <strong>in</strong>crease<br />

from 4000 to 10,000 per cu mm.<br />

The <strong>in</strong>crease is ma<strong>in</strong>ly <strong>in</strong> polymorphonuclear<br />

cells. There is also an<br />

<strong>in</strong>crease <strong>in</strong> the platelet count which may<br />

rise from 150,000 to 500,000/cu mm.<br />

Heart sounds - It is important for the<br />

student <strong>of</strong> obstetrics to review normal<br />

function<strong>in</strong>g <strong>of</strong> the heart <strong>in</strong> the non-pregnant<br />

state. He must familiarize himself<br />

with various heart sounds which are<br />

produced by open<strong>in</strong>g and closure <strong>of</strong><br />

various heart valves. In my op<strong>in</strong>ion it is<br />

not possible to appreciate abnormal heart<br />

sounds and murmurs unless the student<br />

is adequately familiar with normal heart<br />

sounds and physiological changes which<br />

occur <strong>in</strong> the blood volume and shapes <strong>of</strong><br />

the heart and cardiac output dur<strong>in</strong>g<br />

pregnancy.<br />

Fig5.4: Shows two cardiac cycles<br />

open<strong>in</strong>g and clos<strong>in</strong>g <strong>of</strong> valves produce<br />

sounds.<br />

Heart sounds<br />

69<br />

The clos<strong>in</strong>g <strong>of</strong> the mitral and tricuspid<br />

valves (known together as the atrioventricular<br />

valves) at the beg<strong>in</strong>n<strong>in</strong>g <strong>of</strong><br />

ventricular systole cause the first part <strong>of</strong><br />

the "lubb-dub" sound made by the heart<br />

as it beats. Formally, this sound is<br />

known as the First Heart Tone, or S1.<br />

This first heart tone is created by the<br />

closure <strong>of</strong> mitral and tricuspid valve and<br />

is actually a two component sound, M1,<br />

T1.<br />

Second <strong>in</strong>tercostal space, right<br />

sternal border<br />

Aortic<br />

Value<br />

Second and third<br />

<strong>in</strong>tercostal space, left<br />

sternal border<br />

Pulmonary<br />

Value<br />

Mitral Value<br />

Fifth <strong>in</strong>tercostal<br />

space, left<br />

sternal border<br />

Tricuspid<br />

Value<br />

Fifth <strong>in</strong>tercostal<br />

space, midclavicular<br />

l<strong>in</strong>e<br />

Fig5.5: Shows pr<strong>in</strong>cipal areas for<br />

auscultation for heart sounds.<br />

The second part <strong>of</strong> the "lub-dubb" (the<br />

Second Heart Tone, or S2), is caused by<br />

the closure <strong>of</strong> the aortic and pulmonary<br />

valves at the end <strong>of</strong> ventricular systole.<br />

As the left ventricle empties, its pressure<br />

falls below the pressure <strong>in</strong> the aorta, and<br />

the aortic valve closes. Similarly, as the<br />

pressure <strong>in</strong> the right ventricle falls below<br />

the pressure <strong>in</strong> the pulmonary artery, the<br />

pulmonary valve closes. The second<br />

heart sound is also two components, A2<br />

and P2. The aortic valve closes earlier<br />

than the pulmonary valve and they are<br />

audibly separated from each other <strong>in</strong> the<br />

second heart sound. This "splitt<strong>in</strong>g" <strong>of</strong><br />

S2 is only audible dur<strong>in</strong>g <strong>in</strong>halation.<br />

However, some cardiac conduction ab-

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