Book of Medical Disorders in Pregnancy - Tintash
Book of Medical Disorders in Pregnancy - Tintash
Book of Medical Disorders in Pregnancy - Tintash
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pregnancy. The <strong>in</strong>crease <strong>in</strong> volume is<br />
probably due to <strong>in</strong>creased production <strong>of</strong><br />
aldosterone which occurs <strong>in</strong> normal<br />
pregnancy. Estrogens also play some<br />
part <strong>in</strong> <strong>in</strong>creas<strong>in</strong>g this volume.<br />
Blood corpuscles - The white cells <strong>in</strong>crease<br />
from 4000 to 10,000 per cu mm.<br />
The <strong>in</strong>crease is ma<strong>in</strong>ly <strong>in</strong> polymorphonuclear<br />
cells. There is also an<br />
<strong>in</strong>crease <strong>in</strong> the platelet count which may<br />
rise from 150,000 to 500,000/cu mm.<br />
Heart sounds - It is important for the<br />
student <strong>of</strong> obstetrics to review normal<br />
function<strong>in</strong>g <strong>of</strong> the heart <strong>in</strong> the non-pregnant<br />
state. He must familiarize himself<br />
with various heart sounds which are<br />
produced by open<strong>in</strong>g and closure <strong>of</strong><br />
various heart valves. In my op<strong>in</strong>ion it is<br />
not possible to appreciate abnormal heart<br />
sounds and murmurs unless the student<br />
is adequately familiar with normal heart<br />
sounds and physiological changes which<br />
occur <strong>in</strong> the blood volume and shapes <strong>of</strong><br />
the heart and cardiac output dur<strong>in</strong>g<br />
pregnancy.<br />
Fig5.4: Shows two cardiac cycles<br />
open<strong>in</strong>g and clos<strong>in</strong>g <strong>of</strong> valves produce<br />
sounds.<br />
Heart sounds<br />
69<br />
The clos<strong>in</strong>g <strong>of</strong> the mitral and tricuspid<br />
valves (known together as the atrioventricular<br />
valves) at the beg<strong>in</strong>n<strong>in</strong>g <strong>of</strong><br />
ventricular systole cause the first part <strong>of</strong><br />
the "lubb-dub" sound made by the heart<br />
as it beats. Formally, this sound is<br />
known as the First Heart Tone, or S1.<br />
This first heart tone is created by the<br />
closure <strong>of</strong> mitral and tricuspid valve and<br />
is actually a two component sound, M1,<br />
T1.<br />
Second <strong>in</strong>tercostal space, right<br />
sternal border<br />
Aortic<br />
Value<br />
Second and third<br />
<strong>in</strong>tercostal space, left<br />
sternal border<br />
Pulmonary<br />
Value<br />
Mitral Value<br />
Fifth <strong>in</strong>tercostal<br />
space, left<br />
sternal border<br />
Tricuspid<br />
Value<br />
Fifth <strong>in</strong>tercostal<br />
space, midclavicular<br />
l<strong>in</strong>e<br />
Fig5.5: Shows pr<strong>in</strong>cipal areas for<br />
auscultation for heart sounds.<br />
The second part <strong>of</strong> the "lub-dubb" (the<br />
Second Heart Tone, or S2), is caused by<br />
the closure <strong>of</strong> the aortic and pulmonary<br />
valves at the end <strong>of</strong> ventricular systole.<br />
As the left ventricle empties, its pressure<br />
falls below the pressure <strong>in</strong> the aorta, and<br />
the aortic valve closes. Similarly, as the<br />
pressure <strong>in</strong> the right ventricle falls below<br />
the pressure <strong>in</strong> the pulmonary artery, the<br />
pulmonary valve closes. The second<br />
heart sound is also two components, A2<br />
and P2. The aortic valve closes earlier<br />
than the pulmonary valve and they are<br />
audibly separated from each other <strong>in</strong> the<br />
second heart sound. This "splitt<strong>in</strong>g" <strong>of</strong><br />
S2 is only audible dur<strong>in</strong>g <strong>in</strong>halation.<br />
However, some cardiac conduction ab-