Book of Medical Disorders in Pregnancy - Tintash
Book of Medical Disorders in Pregnancy - Tintash
Book of Medical Disorders in Pregnancy - Tintash
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The Stroke Volume - This <strong>in</strong>creases<br />
considerably dur<strong>in</strong>g pregnancy. The<br />
change becomes maximum between 19th<br />
to 20th weeks. From 20 weeks until term<br />
the stroke volume <strong>in</strong>crease rema<strong>in</strong>s<br />
constant. The difference <strong>in</strong> results reported<br />
by various authors is probably<br />
due to the position <strong>of</strong> the patient when<br />
stroke volume and cardiac output was<br />
measured. Some authors <strong>in</strong> the past had<br />
reported a decrease <strong>in</strong> stroke volume<br />
near term, but this is not now accepted<br />
as correct by most authorities.<br />
Cardiac Output - There is 40 per cent<br />
<strong>in</strong>crease <strong>in</strong> cardiac output above normal<br />
by the 28th week. The <strong>in</strong>crease starts<br />
early <strong>in</strong> the first trimester, and cont<strong>in</strong>ues<br />
gradually dur<strong>in</strong>g the second trimester, it<br />
reaches its peak around 28 weeks, and<br />
then rema<strong>in</strong>s at this level till term. Most<br />
authorities <strong>in</strong> the past reported a decl<strong>in</strong>e<br />
<strong>in</strong> cardiac output <strong>in</strong> the last trimester.<br />
This difference is due to the position <strong>of</strong><br />
the patient. When the patient is ly<strong>in</strong>g <strong>in</strong><br />
sup<strong>in</strong>e position, pressure on the <strong>in</strong>ferior<br />
vena cava produces a decrease <strong>in</strong> the<br />
venous return to the right heart and thus<br />
lowers the cardiac output. These workers<br />
made their measurements while the<br />
patient was ly<strong>in</strong>g <strong>in</strong> the lateral position.<br />
An additional <strong>in</strong>crease <strong>in</strong> cardiac output<br />
occurs dur<strong>in</strong>g labour. It is due to an<br />
<strong>in</strong>crease <strong>in</strong> stroke volume caused by<br />
uter<strong>in</strong>e contractions which can squeeze<br />
an extra 400ml <strong>of</strong> blood <strong>in</strong>to the general<br />
circulation.<br />
Blood vessels -<br />
There is generalized vasodilatation due<br />
to decrease <strong>in</strong> tone <strong>of</strong> the smooth muscles<br />
dur<strong>in</strong>g pregnancy. This helps <strong>in</strong><br />
peripheral vasodilatation and thus produces<br />
a great <strong>in</strong>crease <strong>in</strong> the peripheral<br />
blood flow. The ve<strong>in</strong>s are easily dis-<br />
68<br />
tended and therefore there is an <strong>in</strong>crease<br />
<strong>in</strong> the <strong>in</strong>cidence <strong>of</strong> varicosities. The<br />
<strong>in</strong>cidence <strong>of</strong> hemorrhoids is also considerably<br />
<strong>in</strong>creased.<br />
Fig 5.3: Shows <strong>in</strong>side heart structures<br />
Blood volume - This is markedly<br />
<strong>in</strong>creased, reach<strong>in</strong>g its peak around the<br />
end <strong>of</strong> the second trimester where it can<br />
be as much as 48 per cent above the<br />
basel<strong>in</strong>e. There is only a slight <strong>in</strong>crease<br />
dur<strong>in</strong>g the third trimester. This <strong>in</strong>crease<br />
<strong>in</strong> volume is quite disproportionate to the<br />
red cell mass <strong>in</strong>crease. In the first half <strong>of</strong><br />
pregnancy the <strong>in</strong>crease is more <strong>in</strong> the<br />
volume while <strong>in</strong> the second half red cell<br />
mass <strong>in</strong>creases more than the plasma.<br />
The net result is a fall <strong>in</strong> the hematocrit<br />
value, from 41 per cent <strong>in</strong> the nonpregnant<br />
stage to 37 per cent, earlier <strong>in</strong>