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Book of Medical Disorders in Pregnancy - Tintash

Book of Medical Disorders in Pregnancy - Tintash

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The Stroke Volume - This <strong>in</strong>creases<br />

considerably dur<strong>in</strong>g pregnancy. The<br />

change becomes maximum between 19th<br />

to 20th weeks. From 20 weeks until term<br />

the stroke volume <strong>in</strong>crease rema<strong>in</strong>s<br />

constant. The difference <strong>in</strong> results reported<br />

by various authors is probably<br />

due to the position <strong>of</strong> the patient when<br />

stroke volume and cardiac output was<br />

measured. Some authors <strong>in</strong> the past had<br />

reported a decrease <strong>in</strong> stroke volume<br />

near term, but this is not now accepted<br />

as correct by most authorities.<br />

Cardiac Output - There is 40 per cent<br />

<strong>in</strong>crease <strong>in</strong> cardiac output above normal<br />

by the 28th week. The <strong>in</strong>crease starts<br />

early <strong>in</strong> the first trimester, and cont<strong>in</strong>ues<br />

gradually dur<strong>in</strong>g the second trimester, it<br />

reaches its peak around 28 weeks, and<br />

then rema<strong>in</strong>s at this level till term. Most<br />

authorities <strong>in</strong> the past reported a decl<strong>in</strong>e<br />

<strong>in</strong> cardiac output <strong>in</strong> the last trimester.<br />

This difference is due to the position <strong>of</strong><br />

the patient. When the patient is ly<strong>in</strong>g <strong>in</strong><br />

sup<strong>in</strong>e position, pressure on the <strong>in</strong>ferior<br />

vena cava produces a decrease <strong>in</strong> the<br />

venous return to the right heart and thus<br />

lowers the cardiac output. These workers<br />

made their measurements while the<br />

patient was ly<strong>in</strong>g <strong>in</strong> the lateral position.<br />

An additional <strong>in</strong>crease <strong>in</strong> cardiac output<br />

occurs dur<strong>in</strong>g labour. It is due to an<br />

<strong>in</strong>crease <strong>in</strong> stroke volume caused by<br />

uter<strong>in</strong>e contractions which can squeeze<br />

an extra 400ml <strong>of</strong> blood <strong>in</strong>to the general<br />

circulation.<br />

Blood vessels -<br />

There is generalized vasodilatation due<br />

to decrease <strong>in</strong> tone <strong>of</strong> the smooth muscles<br />

dur<strong>in</strong>g pregnancy. This helps <strong>in</strong><br />

peripheral vasodilatation and thus produces<br />

a great <strong>in</strong>crease <strong>in</strong> the peripheral<br />

blood flow. The ve<strong>in</strong>s are easily dis-<br />

68<br />

tended and therefore there is an <strong>in</strong>crease<br />

<strong>in</strong> the <strong>in</strong>cidence <strong>of</strong> varicosities. The<br />

<strong>in</strong>cidence <strong>of</strong> hemorrhoids is also considerably<br />

<strong>in</strong>creased.<br />

Fig 5.3: Shows <strong>in</strong>side heart structures<br />

Blood volume - This is markedly<br />

<strong>in</strong>creased, reach<strong>in</strong>g its peak around the<br />

end <strong>of</strong> the second trimester where it can<br />

be as much as 48 per cent above the<br />

basel<strong>in</strong>e. There is only a slight <strong>in</strong>crease<br />

dur<strong>in</strong>g the third trimester. This <strong>in</strong>crease<br />

<strong>in</strong> volume is quite disproportionate to the<br />

red cell mass <strong>in</strong>crease. In the first half <strong>of</strong><br />

pregnancy the <strong>in</strong>crease is more <strong>in</strong> the<br />

volume while <strong>in</strong> the second half red cell<br />

mass <strong>in</strong>creases more than the plasma.<br />

The net result is a fall <strong>in</strong> the hematocrit<br />

value, from 41 per cent <strong>in</strong> the nonpregnant<br />

stage to 37 per cent, earlier <strong>in</strong>

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