Book of Medical Disorders in Pregnancy - Tintash
Book of Medical Disorders in Pregnancy - Tintash
Book of Medical Disorders in Pregnancy - Tintash
Create successful ePaper yourself
Turn your PDF publications into a flip-book with our unique Google optimized e-Paper software.
Severe pre eclampsia at or remote from<br />
term requires delivery <strong>of</strong> the fetus<br />
(Tables 37.5 and 37.6). Expectant<br />
management under these circumstances<br />
is unusual, and requires careful patient<br />
and family counsel<strong>in</strong>g Laboratory<br />
studies utilized dur<strong>in</strong>g expectant<br />
management <strong>in</strong>clude 24 hours ur<strong>in</strong>e<br />
collections for quantitative prote<strong>in</strong> and<br />
creat<strong>in</strong><strong>in</strong>e clearance, platelet counts,<br />
liver function tests, serum fibr<strong>in</strong>ogen, PT<br />
and PTT<br />
Labor/delivery:<br />
The judicious use <strong>of</strong> fluid therapy and<br />
careful, frequent assessment <strong>of</strong> maternal<br />
vital signs is critical Cont<strong>in</strong>uous<br />
electronic fetal heart rate monitor<strong>in</strong>g is<br />
necessary to evaluate fetal status.<br />
Magnesium sulfate is the drug <strong>of</strong> choice<br />
for seizure prophylaxis (Tables 37.7 and<br />
37.8) Antihypertensive medications are<br />
employed to ma<strong>in</strong>ta<strong>in</strong> blood pressures<br />
below 160/110 mmHg (Table 37.9).<br />
Potential complications <strong>in</strong>clude oliguria,<br />
pulmonary edema, HELLP syndrome<br />
and seizures. Invasive hemodynamic<br />
monitor<strong>in</strong>g is <strong>in</strong>frequently needed. It<br />
should be employed to provide specific<br />
hemodynamic data to effect management<br />
decisions <strong>in</strong> patients who are unstable or<br />
<strong>in</strong> whom the volume status is uncerta<strong>in</strong><br />
Postnatal:<br />
Cont<strong>in</strong>ue seizure prophylaxis <strong>in</strong> preeclamptic<br />
approximately 24 h<br />
postpartum. In patients who have revere<br />
disease <strong>in</strong> the MID trimester, eclampsia<br />
or HELLP syndrome, slow resolution <strong>of</strong><br />
the disease process may dictate close<br />
monitor<strong>in</strong>g and cont<strong>in</strong>uation <strong>of</strong> seizure<br />
prophylaxis for 2-4 days Patients who<br />
still require antihypertensive medication<br />
on discharge from the hospital should be<br />
evaluated weekly. A full work-up should<br />
be <strong>in</strong>itiated for those persistently<br />
65<br />
hypertensive at/or more than 6 weeks<br />
postpartum.<br />
REFERENCES<br />
1. Menon, M.K.K.I. (61) J. Obstet. Gynec.<br />
Brit. Cwith. 68:417.<br />
2. Adams, E.M/ and Macgillivary, 1.<br />
(1961), "Long-term) Effect <strong>of</strong> Preeclampsia<br />
on Blood Pressure", Lancet,<br />
ii, 1371.<br />
3. Lean, T.N. Ratnam, S.S. and<br />
Sivasamboo, R. (1968) : J. Obstet.<br />
Gyne. Brit. Cwith. 75:856<br />
4. Macgillivray, I. (1969) "In modern<br />
Trends <strong>in</strong> Obstetrics - 4" Ed. R.J.<br />
Kellar. Butterworths,<br />
5. London - P. 244 - 245.<br />
6. Macgillivary, I, Rose, G.A. and Rowe,<br />
B. (1969), "Blood Pressure Survey <strong>in</strong><br />
<strong>Pregnancy</strong>", Cl<strong>in</strong>. Sci, 37, 395.<br />
7. Piver, M.S. (1969), "Cl<strong>in</strong>ical Evaluation<br />
<strong>of</strong> Hypertension Six Weeks<br />
postpartum", Sth. med. J., 62,559.<br />
8. Weir, R.J. Pa<strong>in</strong>t<strong>in</strong>, D.B., Robertson,<br />
J.I.S. Tree, M., Fraser, R. and Young J.<br />
(1970), "Ren<strong>in</strong> Angiotens<strong>in</strong> and<br />
Aldosterone Relationships <strong>in</strong> Normal<br />
<strong>Pregnancy</strong>", Proc. roy. Soc. Med.,<br />
63,1101.<br />
9. Bauer, G.E. (1972). "Hypertension and<br />
<strong>Pregnancy</strong>", Med. J. Aust. 2,989.<br />
10. Baird, J.T. (1972), "Parity and<br />
Hypertension", <strong>in</strong> Vital and Health<br />
Statistics, Series 11, No. 38,<br />
Wash<strong>in</strong>gton, D.C.: Public Health<br />
Service, U.S. Government Pr<strong>in</strong>t<strong>in</strong>g<br />
Office.<br />
11. Wilber, J.A. (1972), "The Management<br />
<strong>of</strong> Hypertension Dur<strong>in</strong>g <strong>Pregnancy</strong>", J.<br />
Reprod. Med. 8,53.<br />
12. Freis, E.D. (1973), The Modern<br />
Management <strong>of</strong> Hypertension.<br />
Wash<strong>in</strong>gton, D.C.: Veterans<br />
Adm<strong>in</strong>istration.