Book of Medical Disorders in Pregnancy - Tintash
Book of Medical Disorders in Pregnancy - Tintash
Book of Medical Disorders in Pregnancy - Tintash
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has been carried out. There can be<br />
history <strong>of</strong> over dosage with <strong>in</strong>sul<strong>in</strong> <strong>in</strong><br />
these cases. Blood and ur<strong>in</strong>e sugar and<br />
ketone bodies will help <strong>in</strong> differentiat<strong>in</strong>g<br />
this condition from eclampsia.<br />
In diabetic, coma the patient is<br />
dehydrated and collapsed. Acetone will<br />
be smelt <strong>in</strong> the breath and ur<strong>in</strong>e will<br />
conta<strong>in</strong> sugar and ketones.<br />
Hypoglycemic coma is marked by<br />
collapse, low blood pressure, sweat-<strong>in</strong>g<br />
and low blood sugar. It is result <strong>of</strong> over<br />
dosage <strong>of</strong> <strong>in</strong>sul<strong>in</strong>. Careful search <strong>of</strong> sk<strong>in</strong><br />
for signs <strong>of</strong> hypodermic <strong>in</strong>jection is<br />
essential.<br />
Uremic coma - This is marked by dehydration,<br />
dyspnea, high blood pressure,<br />
hypertensive ret<strong>in</strong>opathy and presence <strong>of</strong><br />
album<strong>in</strong> <strong>in</strong> ur<strong>in</strong>e. The specific gravity <strong>of</strong><br />
ur<strong>in</strong>e is usually <strong>in</strong> the region <strong>of</strong> 1010.<br />
The blood urea will be much elevated.<br />
Hepatic coma - This usually follows a<br />
period <strong>of</strong> prolonged illness. In pre-coma<br />
stage, there may be psychosis which is<br />
accompanied by flapp<strong>in</strong>g tremor. Other<br />
features <strong>of</strong> liver disease such as foetor<br />
hepaticus, jaundice or ascites may be<br />
present.<br />
Hypocalcemic convulsion (tetany) - In<br />
this condition, there is paroxysmal tonic<br />
spasm <strong>of</strong> the hands and feet. Hands<br />
assume conical attitude with f<strong>in</strong>gers<br />
extended at the <strong>in</strong>ter phalangeal jo<strong>in</strong>ts.<br />
They are adducted and slightly flexed at<br />
the metacarpophalangeal jo<strong>in</strong>ts. The thumb<br />
is adducted and the palm hallowed.<br />
The toes are flexed towards the sole.<br />
There is planter flexion and the foot is<br />
<strong>in</strong>verted. When such a convulsion can be<br />
produced by arrest<strong>in</strong>g the circulation <strong>in</strong> a<br />
limb for 3 to 4 m<strong>in</strong>utes (Trousseau's<br />
61<br />
sign) or by percussion <strong>of</strong> the superior<br />
motor or facial nerve which will produce<br />
spasm (Chvostek’s sign) the diagnosis <strong>of</strong><br />
hypocalcemic convulsion can be confirmed.<br />
Poison<strong>in</strong>g:<br />
Any type <strong>of</strong> poison<strong>in</strong>g may result <strong>in</strong><br />
coma and convulsions. This may be<br />
common f<strong>in</strong>d<strong>in</strong>g <strong>in</strong> countries where<br />
quacks and traditional birth atten-dants<br />
use herbal medic<strong>in</strong>es and powders to<br />
relieve labour pa<strong>in</strong>. Carbon Monoxide is<br />
present <strong>in</strong> the coal gas and <strong>in</strong> the fumes<br />
given <strong>of</strong>f by any fire or explosion. It<br />
unites with blood to form carboxyhemoglob<strong>in</strong>,<br />
which is cherry red and<br />
imparts this hue to complexion <strong>of</strong> the<br />
patient. Spectroscopic exam<strong>in</strong>ation <strong>of</strong><br />
blood will con-firm diagnosis. Strychn<strong>in</strong>e<br />
is an alkaloid which is obta<strong>in</strong>ed<br />
from nux vomica seeds. This has powerful<br />
stimulant effect on the sp<strong>in</strong>al cord.<br />
When convulsions are <strong>of</strong> sudden onset<br />
with previous history <strong>of</strong> good health,<br />
poison<strong>in</strong>g should be suspected. In strychn<strong>in</strong>e<br />
poison<strong>in</strong>g the contractions are<br />
violent and are first clonic, later tonic.<br />
The whole body is arched backward or<br />
bends forward or to the side. It does not<br />
commence <strong>in</strong> the lower Jaw muscles as<br />
it does <strong>in</strong> tetanus. Similarly dur<strong>in</strong>g the<br />
<strong>in</strong>terval, the muscles are relaxed.<br />
Alcoholism: The coma is not so deep,<br />
there is marked pallor, sweat<strong>in</strong>g, and<br />
stertorous breath<strong>in</strong>g present. The pupils<br />
are dilated; smell <strong>of</strong> alcohol may be<br />
present. Exam<strong>in</strong>ation <strong>of</strong> blood will show<br />
alcohol content <strong>in</strong> excess <strong>of</strong> 300 mg<br />
percent.<br />
Heat stroke - Hyperpyrexia and absence<br />
<strong>of</strong> sweat<strong>in</strong>g are diagnostic features <strong>of</strong><br />
coma due to heat stroke. Pregnant