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Book of Medical Disorders in Pregnancy - Tintash

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consciousness, tonic and/or clonic<br />

movements <strong>of</strong> extremities, trunk and<br />

face and <strong>in</strong>cont<strong>in</strong>ence <strong>of</strong> ur<strong>in</strong>e and feces.<br />

The family history or patient's past<br />

history may be helpful <strong>in</strong> separat<strong>in</strong>g this<br />

from eclampsia. The signs such as<br />

oedema, prote<strong>in</strong>uria and hypertension<br />

are dist<strong>in</strong>ctly absent <strong>in</strong>cases <strong>of</strong> epilepsy.<br />

Cerebral tumour - When convulsions<br />

are reported with previous history <strong>of</strong><br />

headache, nausea and projectile vomit<strong>in</strong>g;<br />

presence <strong>of</strong> papilledema and raised<br />

cerebrosp<strong>in</strong>al pressure are very suggestive<br />

features <strong>of</strong> cerebral tumor. F<strong>in</strong>al<br />

diagnosis will depend on demonstrat<strong>in</strong>g<br />

the mass by C.T. or other type <strong>of</strong> bra<strong>in</strong><br />

scan.<br />

Head <strong>in</strong>jury:<br />

Inspection and palpation may reveal<br />

bruises and depression <strong>of</strong> the skull.<br />

There may be leakage <strong>of</strong> sp<strong>in</strong>al fluid<br />

from nose or ear.<br />

Sub conjunctival hemorrhage usually<br />

<strong>in</strong>dicates the frac-ture <strong>of</strong> anterior or<br />

middle fossa. Radio-logical evidence <strong>of</strong><br />

fracture <strong>of</strong> skull will confirm the<br />

diagnosis.<br />

Vascular accidents:<br />

Cerebral thrombosis is a common cause<br />

<strong>of</strong> coma. There is usually some <strong>in</strong>dication<br />

<strong>of</strong> a local lesion such as facial<br />

asymmetry deviation <strong>of</strong> eyes or undue<br />

flaccidity <strong>of</strong> arm and leg on one side.<br />

Cerebral Hemorrhage usually results <strong>in</strong><br />

fatal coma. The blood pressure is usually<br />

high, the pulse is slow, the left ventricle<br />

is enlarged and hypertensive ret<strong>in</strong>opathy<br />

may be present.<br />

Intracranial <strong>in</strong>fections<br />

60<br />

Men<strong>in</strong>gitis - Any form <strong>of</strong> men<strong>in</strong>gitis can<br />

cause convulsion. High grade fever,<br />

headache nausea and vomit<strong>in</strong>g with neck<br />

rigidity are highly suggestive. When leukocytes<br />

and organisms are found <strong>in</strong> the<br />

CSF, the diagnosis is def<strong>in</strong>ite.<br />

Fulm<strong>in</strong>at<strong>in</strong>g Men<strong>in</strong>gococcal Me-n<strong>in</strong>gitis<br />

may cause coma and death with<strong>in</strong> 24<br />

hours. The temperature is usually<br />

elevated, stiffness <strong>of</strong> neck and f<strong>in</strong>e<br />

purpuric rash is common. Diagnosis is<br />

made by lumbar puncture which reveals<br />

cloudy fluid conta<strong>in</strong><strong>in</strong>g organism and<br />

polymorph leucocytes.<br />

Cerebral malaria - This tropical disease<br />

can cause convulsions, coma and fever.<br />

The diagnosis will depend on the history<br />

<strong>of</strong> exposure to the disease and presence<br />

<strong>of</strong> parasites <strong>in</strong> the peripheral blood film.<br />

Cerebral malaria is an important cause <strong>of</strong><br />

sudden coma. The temperature may be<br />

normal or high. The spleen may or may<br />

not be enlarged.<br />

Tetanus:<br />

In cases where there is previous history<br />

<strong>of</strong> abrasions or wound <strong>of</strong> sk<strong>in</strong>, tetanus<br />

needs to be ruled out. The earliest<br />

manifestation <strong>in</strong> tetanus is trismus or<br />

tonic spasm <strong>of</strong> the masseter muscles.<br />

This is followed by tetanic spasm <strong>of</strong><br />

other muscles and f<strong>in</strong>ally leads to<br />

episthotonos and risus sardonicus. Dur<strong>in</strong>g<br />

the <strong>in</strong>terval <strong>of</strong> tetanic spasms, the<br />

muscles are rigid.<br />

Hypoglycemic convulsions: These<br />

convulsions tend to occur <strong>in</strong> the early<br />

hours <strong>of</strong> the day, when a meal has been<br />

missed or unwanted physical exertion

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