Book of Medical Disorders in Pregnancy - Tintash
Book of Medical Disorders in Pregnancy - Tintash
Book of Medical Disorders in Pregnancy - Tintash
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differentiat<strong>in</strong>g between chronic<br />
hypertension and pregnancy <strong>in</strong>-duced<br />
hypertension when a patient becomes<br />
hypertensive <strong>in</strong> the early third trimester.<br />
Patients, who require less than 7 mg <strong>of</strong><br />
angiotens<strong>in</strong> II per kilogram <strong>of</strong> body<br />
weight per m<strong>in</strong>ute to elicit a pressure<br />
response at this time, can be diagnosed<br />
as case <strong>of</strong> preeclampsia. The student<br />
must be cautioned here that <strong>in</strong> normal<br />
cl<strong>in</strong>ical practice such tests can not be<br />
done, therefore no attempt should be<br />
made to perform this test. Such cases<br />
should be referred to a referral centre<br />
equipped with these diagnostic facilities.<br />
Chronic hypertension with<br />
superimposed pre eclampsia:<br />
Chronic hypertension with superimposed<br />
pre-eclampsia is the result <strong>of</strong> acute aggravation<br />
<strong>of</strong> the already exist<strong>in</strong>g underly<strong>in</strong>g<br />
hypertension, with the rapid development<br />
<strong>of</strong> edema and prote<strong>in</strong>uria. The<br />
funduscopic f<strong>in</strong>d<strong>in</strong>gs show<strong>in</strong>g re-t<strong>in</strong>al<br />
sheen, hemorrhages, and exudates may<br />
become more prom<strong>in</strong>ent. There is <strong>of</strong>ten<br />
a quick progression to eclampsia, which<br />
may develop before the 30th week <strong>of</strong><br />
gestation. Strict diagnostic criteria are<br />
sometimes difficult to establish but<br />
depend on the follow<strong>in</strong>g.<br />
When documented evidence is available<br />
that the patient had chronic hypertension<br />
along with the evidence <strong>of</strong> a<br />
superimposed acute process, as<br />
demonstrated by elevation <strong>of</strong> systolic<br />
blood pressure by 30 mm Hg or diastolic<br />
blood pressure by 15 to 20 mm Hg<br />
above the base l<strong>in</strong>e on two occasions at<br />
least 6-hours apart. Prote<strong>in</strong>uria and or<br />
edema as observed <strong>in</strong> women with preeclampsia<br />
are also present. The<br />
development <strong>of</strong> any one <strong>of</strong> the three<br />
signs <strong>of</strong> superimposed preeclampsia, that<br />
53<br />
is, worsen<strong>in</strong>g hyper-tension, prote<strong>in</strong>uria,<br />
or edema, may al-one if severe enough,<br />
justify the diagnosis <strong>of</strong> superimposed<br />
preeclampsia. However, the diagnosis<br />
should re-quire the presence <strong>of</strong><br />
accelerated hyper-tension accompanied<br />
by at least one <strong>of</strong> the two other signs.<br />
If the gravida with chronic hypertension<br />
requires less than 7 mg/kg/m<strong>in</strong>ute <strong>of</strong><br />
angiotens<strong>in</strong> II to elicit a 20 mm Hg<br />
<strong>in</strong>crease <strong>in</strong> diastolic blood pressure, it is<br />
likely that she has superimposed preeclampsia.<br />
Normal<br />
blood<br />
flow<br />
Carotid<br />
Arteries<br />
Bra<strong>in</strong><br />
Decreased<br />
Blood flow<br />
Fig4.6: Shows bra<strong>in</strong> vessels exposed.<br />
Latent or transient hypertension:<br />
The category <strong>of</strong> 'Intent or transient<br />
hypertension <strong>in</strong>cludes only those patients<br />
whose transient elevations <strong>of</strong> blood pressure<br />
are observed dur<strong>in</strong>g labor or <strong>in</strong> the<br />
early puerperium.<br />
Their illnesses may range widely from<br />
mild preeclampsia to latent or early<br />
vascular hypertension.<br />
Management <strong>of</strong> pregnancy <strong>in</strong>duced<br />
hypertension:<br />
The management <strong>in</strong>cludes prevention<br />
and therapeutic treatment.