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Book of Medical Disorders in Pregnancy - Tintash

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<strong>of</strong> the cells favores the reduction <strong>of</strong> the<br />

<strong>in</strong>tracellular ferric iron to the soluble<br />

ferrous form and its direct diffusion out<br />

<strong>of</strong> the mucosal cell <strong>in</strong>to the blood.<br />

Iron excretion: The excretion <strong>of</strong> iron<br />

occurs <strong>in</strong> very m<strong>in</strong>ute amounts, chiefly<br />

through the ur<strong>in</strong>e (0.4 mg daily) and<br />

stools (0.8 mg daily). Excretion through<br />

bile, desqua-mation <strong>of</strong> sk<strong>in</strong> cells and<br />

sweat is very m<strong>in</strong>ute. The average diet<br />

conta<strong>in</strong>s quite excesses <strong>of</strong> iron. The<br />

losses are also m<strong>in</strong>imal <strong>in</strong> health<br />

therefore iron deficiency states almost<br />

never occur <strong>in</strong> the males. When there is<br />

abnormal loss <strong>of</strong> blood or iron or<br />

deficient diet is consumed for longer<br />

periods. Anaemia may occur. In the<br />

female the situation is quite different as<br />

there can be excessive loss <strong>of</strong> menstrual<br />

blood and the depletion <strong>of</strong> iron stores by<br />

pregnancy and lactation.<br />

Fig 1.2: Shows normal red blood<br />

corpuscles<br />

Cl<strong>in</strong>ical features: When iron deficiency<br />

occurs, lassitude and exhaustion are<br />

quite early manifestations. These result<br />

due to failure <strong>of</strong> enzyme systems <strong>in</strong> the<br />

body.<br />

Presentation symptoms:<br />

Often asymptomatic but fatigue, dyspnea<br />

and Signs: <strong>of</strong> Pallor.<br />

Can be present Investigations Hb<br />

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