14.05.2013 Views

Book of Medical Disorders in Pregnancy - Tintash

Book of Medical Disorders in Pregnancy - Tintash

Book of Medical Disorders in Pregnancy - Tintash

SHOW MORE
SHOW LESS

Create successful ePaper yourself

Turn your PDF publications into a flip-book with our unique Google optimized e-Paper software.

embark upon a pregnancy. Severe airflow<br />

limitation, with lung function measurements<br />

below 60% <strong>of</strong> predicted, leads<br />

many units to advise CF women aga<strong>in</strong>st<br />

becom<strong>in</strong>g pregnant although, as Canny<br />

et al demonstrate, more seriously limited<br />

women can come through pregnancy<br />

successfully.60 it is vital that the developpment<br />

<strong>of</strong> edema, headaches and<br />

mental confusion is recognized as respiratory<br />

failure and not mistaken for preeclampsia.<br />

After a pregnancy, women with CF have<br />

worse lung function than before, but this<br />

deterioration is no greater than that seen<br />

<strong>in</strong> non pregnant CF women over a 9month<br />

period.<br />

7. Influenza and the common cold:<br />

Influenza is generally self limited <strong>in</strong><br />

healthy young adults. However, if pneumonia<br />

develops, it can be life-threaten<strong>in</strong>g<br />

and may be more severe <strong>in</strong> pregnancy.25.<br />

The <strong>in</strong>fluenza vacc<strong>in</strong>e is recommended<br />

for all women who will be<br />

<strong>in</strong> the second or third trimester <strong>of</strong> pregnancy<br />

dur<strong>in</strong>g the <strong>in</strong>fluenza season.<br />

Because <strong>in</strong>fluenza does not usually result<br />

<strong>in</strong> a viremia, transplacental <strong>in</strong>fection<br />

rarely occurs. Concern has been raised<br />

about a possible association between <strong>in</strong>fluenza<br />

<strong>in</strong> early pregnancy and anencephaly,<br />

but there is no firm evidence.<br />

Influenza-specific antibody is transmitted<br />

to the fetus <strong>in</strong> utero and protects<br />

the newborn. However, susceptible newborns<br />

are at <strong>in</strong>creased risk for <strong>in</strong>fluenza,<br />

with manifestations rang<strong>in</strong>g from mild<br />

coryza to sepsis. If <strong>in</strong>fluenza occurs <strong>in</strong><br />

late pregnancy, delivery should be delayed<br />

until the mother has recovered, if<br />

possible, to allow the newborn to acquire<br />

transplacental antibodies. This usually<br />

107<br />

occurs by five days after the onset <strong>of</strong><br />

symptoms. The common cold is the most<br />

frequent acute illness affect<strong>in</strong>g humans.<br />

REFERENCES:<br />

1. Freeth A: Rout<strong>in</strong>e x-ray<br />

exam<strong>in</strong>ation <strong>of</strong> the chest at an<br />

antenatal cl<strong>in</strong>ic. Lancet 1:287,<br />

1953.<br />

2. Krumholz RA, Echt CR, Ross JC:<br />

Pulmonary diffus<strong>in</strong>g capacity,<br />

capillary blood volume, lung<br />

volumes, and mechanics <strong>of</strong><br />

ventilation <strong>in</strong> early and late<br />

pregnancy. J Lab Cl<strong>in</strong> Med 63:648,<br />

1964.<br />

3. Hopwood HG Jr: Pneumonia <strong>in</strong><br />

pregnancy. Obstet Gynecol 25:875,<br />

1965.<br />

4. Andersen GJ, James GB, Mathers<br />

NP, et al: The maternal oxygen<br />

tension and acid-base status dur<strong>in</strong>g<br />

pregnancy. J Obstet Gynaecol Br<br />

Commonw 76:16, 1969.<br />

5. Bahna SL, Bjerkedal T: The course<br />

and outcome <strong>of</strong> pregnancy <strong>in</strong><br />

women with bronchial asthma.<br />

Acta Allergol 27:397, 1972.<br />

6. Alaily AB, Carrol KB: Pulmonary<br />

ventilation <strong>in</strong> pregnancy. Br J<br />

Obstet Gynaecol 85:518, 1978.<br />

7. American Thoracic Society:<br />

Diagnostic standards and<br />

classification <strong>of</strong> tuberclosis. Am<br />

Rev Respir Dis 142:725, 1990.<br />

8. Elias S, Annas GJ, Simpson JL:<br />

Carrier screen<strong>in</strong>g for cystic<br />

fibrosis: Implications for obstetric<br />

and gynecologic practice. Am J<br />

Obstet Gynecol 164:1077, 1991.<br />

9. Bartlett, JG, Mundy, LM:<br />

Community-acquired pneumonia.<br />

N Engl J Med 333:1618, 1995.<br />

10. Frangolias DD, Nakielna EM,<br />

Wilcox PG: <strong>Pregnancy</strong> and cystic

Hooray! Your file is uploaded and ready to be published.

Saved successfully!

Ooh no, something went wrong!