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Book of Medical Disorders in Pregnancy - Tintash

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Chapter No: 1<br />

Anaemia <strong>in</strong> pregnancy:<br />

The <strong>in</strong>crease <strong>in</strong> plasma volume causes<br />

hemodilution <strong>in</strong> a pregnant woman<br />

which can give artificially low haemoglob<strong>in</strong>.<br />

The WHO advice that haemoglob<strong>in</strong><br />

levels should not fall below<br />

11.0g/dl and certa<strong>in</strong>ly haemoglob<strong>in</strong> concentrations<br />

<strong>of</strong> less than 10.5g/dl should<br />

be regarded as abnormal.<br />

When the hemoglob<strong>in</strong> falls below 10<br />

grams per hundred milliliters <strong>of</strong> blood<br />

dur<strong>in</strong>g pregnancy, true anemia is said to<br />

be present. A fall <strong>in</strong> hemoglob<strong>in</strong> level<br />

without a concomitant fall <strong>in</strong> the mean<br />

corpuscular hemoglob<strong>in</strong> concentration is<br />

considered to be due to hemodilution.<br />

But when reduction <strong>in</strong> hemoglob<strong>in</strong> as<br />

well as mean corpuscular hemoglob<strong>in</strong><br />

concentration occurs, this is always due<br />

to real anaemia.<br />

Physiological hemodilution:<br />

This can reduce the hemoglob<strong>in</strong> level to<br />

as low as 80 per cent or 10 grams per<br />

cent. The total mass <strong>of</strong> circulat<strong>in</strong>g<br />

hemoglob<strong>in</strong> is not dim<strong>in</strong>ished by this<br />

physiological dilution process. If the<br />

bone narrow is provided with sufficient<br />

amounts <strong>of</strong> iron.<br />

It can then produce more red cells, and<br />

hemoglob<strong>in</strong> will <strong>in</strong>crease <strong>in</strong> proportion<br />

to the <strong>in</strong>crease <strong>in</strong> plasma volume. The<br />

mass <strong>of</strong> circulat<strong>in</strong>g hemoglob<strong>in</strong> is<br />

greater than <strong>in</strong> normal non pregnant<br />

woman.<br />

Whether this is advantageous to the<br />

patient is not clear, but it appears to do<br />

no harm, therefore iron supplementation<br />

dur<strong>in</strong>g pregnancy rema<strong>in</strong>s an accepted<br />

ANAEMIA IN PREGNANCY<br />

sound practice. The student is referred to<br />

consult Chapter on nutrition <strong>in</strong> pregnancy<br />

concern<strong>in</strong>g value <strong>of</strong> rout<strong>in</strong>e iron<br />

supplementation.<br />

Mild anaemia<br />

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