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Yield: 83 %. 1 H NMR (300 MHz, DMSO-d6): δ = 10.80 (br s, 1H), 7.88 (s, 1H), 7.83
(d, J = 1.7 Hz 1H), 7.58 (d of d, J = 8.3, 1.7 Hz, 1H), 7.52 (s, 1H), 7.49 (s, 1H), 6.13
(br s, 1H), 4.38 (t, J = 6.98 Hz, 2H), 3.15 (m, 2H), 2.57 (t, J = 7.51 Hz, 2H), 2.06 (m,
2H), 1.58 (m, 2H), 0.89 (t, J = 7.51 Hz, 3H). 13 C NMR (75.5 MHz, DMSO-d6): δ =
150.0, 146.6, 135.1, 131.0 (×2), 130.3 126.8 (×2), 124.8, 123.5, 121.7, 54.8, 46.9,
30.0, 27.0, 22.2, 13.5. HRMS (EI) C17H20Cl2N6, calcd 378.1127., found : 378.1114.
5-(4-Bromophenyl)-N-(2-(4-propyl-1H-1,2,3-triazol-1-yl)ethyl)-1H-imidazol-2amine
(BS-304)
Br
N
H
N
N
H
N
N
N
C 3H 7
Yield: 95 %. 1 H NMR (300 MHz, DMSO-d6): δ = 10.63 (br s, 1H), 7.87(s, 1H), 7.62
(m, 2H), 7.48 (d , J = 8.6 Hz, 2H), 7.17 (s, 1H), 5.98 (t, J = 5.3 Hz, 1H), 4.59 (t, J =
6.04 Hz, 2H), 3.66 (m, 2H), 2.61 (t, J = 7.44 Hz, 2H), 1.62 (m, 2H), 0.94 (t, J = 7.21
Hz, 3H). 13 C NMR (75.5 MHz, DMSO-d6): δ = 150.5, 146.5, 134.6, 131.0 (×3),
125.4 (×2), 122.0 (×2), 117.4, 48.9, 42.9, 27.0, 22.2, 13.6. HRMS (EI) C16H19BrN6,
calcd 374.0855., found: 374.0844.
5-(4-Bromophenyl)-N-(3-(4-propyl-1H-1,2,3-triazol-1-yl)propyl)-1H-imidazol-2amine
(BS-305)
Br
N
N
H
N
H
N
N N
C 3H 7
Yield: 74 %. 1 H NMR (300 MHz, DMSO-d6): δ = 10.59 (br s, 1H), 7.89 (s, 1H), 7.55
(d , J = 8.1 Hz, 2H), 7.42 (d , J = 8.4 Hz, 2H), 7.11 (s, 1H), 5.93 (t, J = 5.25 Hz, 1H),
4.38 (t, J = 6.83 Hz, 2H), 3.14 (m, 2H), 2.48 (t, J = 7.62 Hz, 2H), 2.06 (m, 2H), 1.58
(m, 2H), 0.90 (t, J = 7.35 Hz, 3H). 13 C NMR (75.5 MHz, DMSO-d6): δ = 151.1,
146.6, 134.6, 131.0 (×3), 125.4 (×2), 121.7 (×2), 117.4, 47.9, 30.0, 27.0 (×2), 22.2,
13.5. HRMS (EI) C17H21BrN6, calcd 388.1011., found: 388.1023.