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5-(4-Bromophenyl)-N-(2-(4-heptyl-1H-1,2,3-triazol-1-yl)ethyl)-1H-imidazol-2amine
(BS-277)
Br
N
H
N
N
H
N
N
N
C 7H 15
Yield: 73 %. 1 H NMR (300 MHz, DMSO-d6): δ = 10.56 (br s, 1H), 7.82 (s, 1H), 7.59
(d, J = 8.2 Hz, 2H), 7.42 (d, J = 7.9 Hz, 2H), 7.13 (s, 1H), 5.93 (br s, 1H), 4.51 (t, J =
5.90 Hz, 2H), 3.60 (m, 2H), 2.57 (d, J = 7.7 Hz, 2H), 1.57 (m, 2H), 1.25 (m, 8H), 0.85
(t, J = 6.9 Hz, 3H). 13 C NMR (75.5 MHz, DMSO-d6): δ = 150.5, 146.7 (×2), 131.0
(×3 ), 125.3, 121.9 (×2), 117.4, 104.1, 48.9, 42.9, 31.1, 28.9, 28.5, 28.4, 25.0, 22.0,
13.9. HRMS (EI) C20H27BrN6, calcd 430.1481, found : 430.1488.
5-(4-Bromophenyl)-N-(3-(4-(4-pentylphenyl)-1H-1,2,3-triazol-1-yl)propyl)-1Himidazol-2-amine
(BS-278)
Br
N
N
H
N
H
N
N N
C 5H 11
Yield: 80 %. 1 H NMR (300 MHz, DMSO-d6): δ = 10.58 (br s, 1H), 8.55 (s, 1H), 7.72
(d, J = 8.06 Hz, 2H), 7.53 (d, J = 8.06 Hz, 2H), 7.38 (d, J = 8.27 Hz, 2H), 7.23 (d, J =
8.06 Hz, 2H), 7.11 (s, 1H), 5.96 (m, 1H), 4.47 (t, J = 6.57 Hz, 2H), 3.19 (m, 2H), 2.59
(t, J = 7.63 Hz, 2H), 2.14 (m, 2H), 1.59 (m, 2H), 1.30 (m, 4H), 0.86 (t, J = 6.78 Hz,
3H). 13 C NMR (75.5 MHz, DMSO-d6): δ = 146.3, 142.9, 131.0 (×2), 128.7 (×4),
128.3, 125.4, 124.0 (×4), 121.0, 117.3 (×2), 47.3, 39.9, 34.8, 30.8, 30.5, 30.6, 21.9,
13.8. HRMS (EI) C25H29BrN6. calcd.492.1637, found: 492. 1621.
5-(3,4-Dichlorophenyl)-N-(2-(4-(4-heptylphenyl)-1H-1,2,3-triazol-1-yl)ethyl)-1Himidazol-2-amine
( BS-279)
Cl
Cl
N
H
N
N
H
N
N
N
C 7H 15