Download het volledig rapport (302 p.) - KCE

KCE reports vol. 6A Prenatale zorg 68
Study Ref Population Intervention Outcomes Results
to 2.67)
Comments Study
type
Mahomed,
2001
4 [74] 8 RCTs (5449
pregnant women
with haemoglobin
level > 10 g/dl
Iron and folate
supplementation vs. no iron
and folate or placebo
Haemoglobin
Measures of iron
and folic acid
status
Preterm delivery (1 RCT, n =
2694): Peto OR 1.41 (95% CI 0.94
to 2.12)
Low birth weight (1 RCT, n =
2694): Peto OR 1.12 (95% CI 0.72
to 1.75)
SGA (1 RCT, n = 2690): Peto OR
1.10 (95% CI 0.79 to 1.52)
Admission to neonatal unit (1
RCT, n = 2694): Peto OR 1.06
(95% CI 0.80 to 1.40)
Congenital malformations (1 RCT,
n = 2694): Peto OR 1.01 (95% CI
0.77 to 1.33)
Stillbirths and deaths in first week
of life (1 RCT, n = 2694): Peto
OR 0.33 (95% CI 0.11, 0.99)
Side effects in mothers (3 RCTs, n
= 7098): Peto OR 0.41 (95% CI
0.34 to 0.50)
Low (< 10 g or 10.5 g)
predelivery Hb (6 RCTs, n =
1099): Peto OR 0.19 (95% CI 0.13
to 0.27)
Low predelivery serum iron (3
EL
SR 1a