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KCE reports vol. 6A Prenatale zorg 66
Study Ref Population Intervention Outcomes Results Comments Study
type
hours during formed singletons
pregnancy was lower than
- 2% more expected (less than
cardiotocographie 3/ 1000) what may
s
be due to the
- 1% more
admissions
Hawthorne effect
Klinische biologie
1. Haematology
1.a. Haemoglobin, ferritin and MCV-MCH-MCHC
Is anaemia in pregnancy associated with adverse maternal and perinatal outcomes?
Study Ref Population Intervention Outcomes Results Comments Study
Zhou et
al., 1998
4 [272] 829 pregnant women in
China from 1991 to 1992
Women divided into 6 groups
based on their 1 st trimester Hb
concentrations (< 9.0, 9.0 to
9.9, 10.0 to 10.9, 11.0 to 11.9,
12.0 to 12.9, º13.0 g/dl)
Vitamin C, iron sulphate and
folic acid treatment was
offered to all women with Hb
levels < 11 g/dl (defined as
anaemia)
Prevalence of anaemia
Based on initial Hb
concentrations:
Risk of low birth weight
Risk of preterm birth
Risk of SGA
49% at enrolment, 66% in 2 nd
trimester, 67% in 3 rd trimester
Low birth weight: > 11.9 g/dl,
NS; 10.0 to 10.9, RR 2.7 (95%
CI 1.01 to 7.39); 9.0 to 9.9, RR
3.3 (95% CI 1.09 to 9.77); <
9.0, RR 3.0 (95% CI 0.60 to
14.76)
Preterm birth: >11.9 g/dl, NS;
10.0 to 10.9, NS; 9.0 to 9.9, RR
2.6 (95% CI 1.17 to 5.90); <
9.0, RR 3.7 (95% CI 1.36 to
10.23)
SGA: NS for all groups
EL
EL
type
CH 2b