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KCE reports vol. 6A Prenatale zorg 59
Study Ref Population Intervention Outcomes Results
Maternal age over 40 years and
Comments Study
type
History of primiparous OR 2.17, 95% CI
previous pre- 1.36 to 3.47; maternal age over
eclampsia 40 years and multiparous OR
2.05, 95% CI 1.47 to 2.87 (15
studies)
Rosenberg
et al., 2003
62 Pregnant
women
Data from
the 1998-
1999 New
Five categories of
prepregnancy weight were
constructed and used to
predict gestational diabetes,
preeclampsia, caesarean
delivery, very low birth
Family history of
preeclampsia
Underlying
medical
conditions
Multiple
pregnancy
BMI
Gestational
diabetes
Pre-eclampsie
Caesarean
Pre-eclampsia in first pregnancy
OR 8.23, 95% CI 6.49 to 10.45;
pre-eclampsia in second
pregnancy OR 11.51, 95% CI
5.76 to 22.98 (10 studies)
Positive family history of preeclampsia
OR 5.27, 95% CI 1.57
to 17.64 (1 cohort study)
Pre-existing diabetes (type 1)
OR 4.53, 95% CI 3.30 to 6.23
(5 studies)
Multiple pregnancy (regardless
of parity) OR 2.76, 95% CI 1.99
to 3.82 (9 studies)
BMI over 35 at booking OR
2.29, 95% CI 1.61 to3.24 (2
studies)
Compared to women weighing
45-67kg, women with
prepregnancy weight > 136kg
had the highest OR for:
- gestational diabetes
The vital statistics files used
for this study are known to
have limitations, including
uneven and invalid reporting
Retrospective
EL
CH 2b