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KCE reports vol. 6A Prenatale zorg 228
Study Ref Population Intervention Outcomes Results Comments Stud
y
than those who had
couple screening.
After delivery most
women remembered their
test results and their
meaning, but 21% of those
with negative test results
of couple testing had
forgotten that repeat
testing would be advisable
if they had a pregnancy
with a new partner.
What is the cost-effectiveness/benefit of carrier screening?
Study Ref Population Intervention Outcomes Results Comments Study
Wildh
agen
et al.,
1998
104 35 studies published
between 1997 and 1996:
target population of the
different strategies:
Hypothetical newborns
Couples in
preconceptional and
postconceptional
situations and pupils
(the Netherlands)
Assessment of costeffectiveness
of six screening
strategies for CF gene
carrier versus no CF gene
carrier screening (no CF
gene carrier screening=
comparator)
Six screening strategies:
Prenatal single entry two
steps (SETS) couple
screening
Prenatal double entry two
Costs and benefits Screening cost / detected
carrier couple:
For strategy 1:
£ 58,000
For strategy 2:
£ 70,000
For strategy 3:
£ 69,000
For strategy 4:
£ 80,000
For strategy 5:
£ 85,000
For strategy 6:
Estimated cost at 1996
prices
Type
type
EL
RV 2
(R
CT
´s ?
)
EL