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Download het volledig rapport (302 p.) - KCE

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<strong>KCE</strong> reports vol. 6A Prenatale zorg 208<br />

Study Ref Population Intervention Outcomes Results Comments Study<br />

type<br />

from 1980 to 1999 intracardiac focus,<br />

on Medline only echogenic bowel, renal<br />

Choroid plexus cyst (95%<br />

pyelectasis, shortened<br />

CI):<br />

humerus, shortened<br />

Sensitivity 0.01 (0.0 to<br />

femur, and fetal structural<br />

0.03)<br />

malformations) to detect<br />

Specificity 0.99 (0.97 to<br />

DownÊs syndrome fetuses<br />

1.0)<br />

Fetal loss 4.3<br />

Femur length (95% CI):<br />

Sensitivity 0.16 (0.05 to<br />

0.40)<br />

Specificity 0.96 (0.94 to<br />

0.98)<br />

Fetal loss 1.2<br />

Humerus length (95% CI):<br />

Sensitivity 0.09 (0.0 to<br />

0.60)<br />

Specificity 0.97 (0.91 to<br />

0.99)<br />

Fetal loss 1.9<br />

Echogenic bowel (95% CI):<br />

Sensitivity 0.04 (0.01 to<br />

0.24)<br />

Specificity 0.99 (0.97 to<br />

1.0)<br />

Fetal loss 1.0<br />

Echogenic intracardiac focus<br />

(95% CI):<br />

Sensitivity 0.11 (0.06 to<br />

0.18)<br />

EL

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