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KCE reports vol. 6A Prenatale zorg 202
Study Ref Population Intervention Outcomes Results Comment
s
1. f. Umbilical and uterine artery Doppler ultrasound
At 28 weeks, compared with women with
cervical lengths above the 75th percentile:
women at or below 75% (CL40 mm) had RR 2.8,
95% CI 1.41 to 5.56 women at or below 5o%
(CL 35 mm) had RR 3.52, 95% CI 1.79 to 6.92
women at or below 25% (CL30 mm) had RR
5.39, 95% CI 2.82 to 10.28
women at or below 10% (CL26 mm) had RR
9.57, 95% CI 5.24 to 17.48
women at or below 5% (CL22 mm) had RR
13.88, 95% CI 7.68 to 25.10
women at or below 1% (CL13 mm) had RR
24.94, 95% CI 13.81 to 45.04
Sensitivity for at 24 and 28 weeks for less than
or equal to 30 mm CL: 54% and 70%
Specificity for at 24 and 28 weeks for less than
or equal to 30 mm CL: 76% and 69%
What is the effect of Doppler ultrasound on perinatal outcomes?
Study Ref Population Intervention Outcomes Results Comment
Bricker and
Neilson,
2001
4
[575]
5 RCTs, 14,388
pregnant women
Routine Doppler ultrasound vs.
no/concealed/selective Doppler
ultrasound
Antenatal
admission
Further Doppler
ultrasound
Birth weight
Antenatal admission: (3 RCTs, n = 9359)
Peto OR 1.05, 95% CI 0.95 to 1.15
Further Doppler ultrasound: (1 RCT, n =
3898) Peto OR 1.57 95% CI 1.30 to 1.90
Birth weight: (mean, SD) (1 RCT, n = 2016)
s
Study
type
EL
Study
type
EL
SR 1a