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KCE reports vol. 6A Prenatale zorg 200
Study Ref Population Intervention Outcomes Results Comments Study type EL
Hill et al., 1995 4 [555] 1252 pregnant
women from a
womenÊs hospital
in the USA
measured with
electronic
calipers
Transvaginal
ultrasound
performed
between 9 and
13 weeks of
gestation. The
distance from the
edge of the
placenta to the
internal cervical
os was measured
with electronic
calipers
placenta praevia
at birth
Sensitivity and
specificity
Positive
predictive value
(PPV) with 15mm
cutoff
Number of
women with
placenta at or
over internal
cervical os
between 9 and
13 weeks
Number of
women with
placenta praevia
at birth
Sensitivity: 100%,
95% CI 48 to 100
Specificity: 99.4%,
95% CI 99.1 to
99.6
In all 5 women,
placenta
extended 15mm
or more over the
internal os at 18
to 23 weeks
PPV: 19%, 95%
CI 6 to 38
77/1252 (6.2%)
had placenta at
or over internal
os
4/1252 (0.32%)
had placenta
praevia at time of
birth
In all 4 women,
the placenta
extended more
than 1.6 cm over
the internal os by
transvaginal
ultrasound at 9
to 13 weeks.
CSS 3