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KCE reports vol. 6A Prenatale zorg 178
Study Ref Population Intervention Outcomes Results Comments Study
type
borderline GDM (n = 115)
Group 4 56 (1.9%)
Wu Wen et
al., 2000
4 [492] 1,729,225 pregnant
women and
1,738,863 infants
from 1984 to 1997
in Canada
Group 3: false positive
group (positive result on
GCT, normal result on
OGTT) (n = 580)
Group 4: negative
screenees (less than 7.8
mmol/l on GCT and normal
result on OGTT) (n =
2940)
Universal screening after
guidelines introduced in
1985 vs. one area where no
universal screening was
implemented and
retrospective analysis of
medical records by ICD-9
codes
Number of women
diagnosed with
GDM
Pregnancy
complications in
areas of universal
screening vs. no
universal screening
Pre-eclampsia:
Group 1 12 (8.4%)
Group 2 10 (8.7%)
Group 3 31 (5.4%)
Group 4 144 (4.9%)
Caesarean:
Group 1 48 (33.6%)
Group 2 34 (29.6 %)
Group 3 136 (23.9%)
Group 4 585 (20.2%)(
In multivariate model,
caesarean vs. spontaneous
vaginal delivery in Group 4 vs.
Group 1: OR 2.2 (95% CI 1.3
to 3.7)
Overall: 38,274 women with
GDM; an increase of 0.3% in
1984 to 2.7% in 1996; universal
screening: 1.6% in 1990 to 2.2%
in 1996 vs. 1.4% to 1.0 in no
screening area
Caesarean section: 18.8% vs.
18.9%
Pre-eclampsia: 2.9% vs. 3.5%
Polyhydramnios: 0.3 vs. 0.5
Amniotic infection: 0.9 vs. 0.5
EL
CS 3